References concerning possible causes of early preeclampsia have been reviewed. The urgency of the problem, the early pre-eclampsia formation mechanisms have been highlighted. A short review of the predictors of early pre-eclampsia: soluble fms-tyrosine kinase-1, soluble endoglin, pregnancy-associated plasma protein A, inhibin A, alpha-fetoprotein, unconjugated estriol is presented. Given early development of early pre-eclampsia at the placenta formation stage placental markers of pre-eclampsia should be checked.

Post-thrombotic disease is still a severe medical and social problem, despite the modern advances in medicine. This paper describes methods of research and treatment for post-thrombotic disease patients. The medicine advances related to post-thrombotic disease treatment have been evaluated.

The study considers the capabilities of high-information multispiral computed tomography and magnetic resonance imaging methods in identifying and studying the course of tuberculosis in 425 patients against the background of terminal HIV infection for the period from 2006 to 2016. X-ray morphological signs of isolated tuberculous lung lesions have been observed in 381 patients (91 %), a generalized form has been found in 154 patients (36 %). The X-ray morphological features of internal organ and system tuberculosis in terminal HIV patients have been determined.

The mortality rate in infectious endocarditis (IE) patients in Surgut in 2006-2013 has been analyzed. The essential IE identification through surgery or autopsy has been as high as 25…35 %. In 8 cases (47.1 %) the autopsy revealed pathomorphological signs of diffuse endocarditis with secondary cardiac cavity dilatation. However, only half of the patients have been diagnosed with IE. The information would facilitate better disease severity estimation and dismal prognosis.

In this paper we present a clinical case of successful extracorporeal membrane oxygenation application to a patient suffering from acute myocardial infarction complicated with acute cardiopulmonary failure, who after myocardial revascularisation initially was not responding to invasive lung ventilation and inotropic medical therapy.

The paper studies the cardiovascular system of primary school children based on the adaptation index, Ruffier index (indicates the cardiovascular system endurance) and Robinson index (a heart work load measure). It has been shown that the proposed tests are suitable for regular schoolchildren checkups since no extra equipment is required.

The paper contains an overview of the most widespread parasitic diseases in the population of Ternopil region, Ukraine. Areas most at least affected in 2010-2014 have been identified. It has been found that that the most common invasive diseases are ascariasis, enterobiasis, trichocephalosis. Among the protozoal diseases the most common one is lambliosis. In most cases the number of patients infected with lamblii is 6-15 cases per 100,000. However, in certain years there have been outbreaks.

At the turn of the 20th century the mortality rate in HIV patients at Khanty-Mansi Autonomous Okrug - Ugra increased annually. Thus study is a retrospective analysis of statistical data and medical records. A HIV mortality rate increase caused by both HIV and other reasons has been found. A major contributor to the mortality rate increase in the region is the growth of HIV-infected patients and more severe clinical HIV outcomes. A higher mortality rate in senior HIV-infected patients has also been found.

Modern infrared thermography applicability (focal plane array-based infrared thermography) to the studies of physiological peculiarities in northerners subjected to short-term or prolonged stay in the Extreme North conditions is discussed. The results obtained in humans and laboratory animals in the moderate climate Russian zone are discussed.

The study objective is assessing the hepatoprotective properties of the RNA-containing drug RN-13 with a model of acute CLL₄ induced hepatitis in rats. Female rats were used to evaluate hepatoprotective properties of the RNA-containing drug RN-13 42. RN-13 increases the survival rate of animals with acute tetrachloromethane hepatitis. The hepatoprotective properties of RN-13 were confirmed by biochemical and morphological data. RN-13 helps reducing the activity of alanine aminotransferase, which indicates its ability to limit cytolysis syndrome. Morphological studies confirm the ability of RN-13 to prevent liver tissue destruction, preserve the radial structure of the hepatic lobes, and limit the development of hydropic and fatty degeneration.