The paper summarizes major skin features of HIV-infection, hepatitis C and offers their brief description. The major types of subordinate dermatoses are presented as a table.

The goal of the research is to evaluate the results and prospects of magnetic resonance phlebography (MR-phlebography) as a screening method that allows todescribe the anatomy of the veins of the retroperitoneal space. The MR-phlebography data from 25 patients has been analyzed. Three types of collateral outflow in the case of lesion of the inferior vena cava are marked out: poster to the abdominal cavity was called retroperitoneal, anteperitoneal outflow - along the anterior wall of the abdomen. In one case in the patient with occlusion of the inferior vena cava observed cava-рorto-caval anastomoses, which has been called an intraperitoneal type of collateral compensation.

A retrospective study of women who had the clinical manifestations of preeclampsia before the 28th week of pregnancy was performed. The somatic, gynaecological and obstetric anamnesis, the course of pregnancy in the first and second trimesters, the degree of proteinuria and terms of delivery, the mass of children at birth were analyzed. According to the results of the study, it was established that the women with the existing pathology of the cardiovascular system and the pathology of kidneys having a history of preeclampsia occurring before 34 weeks of gestation, first-mother women should be included in the high-risk group.

In the paper the results analysis of the 10-year experience of treating 80 patients with complications of diverticular disease of colon is performed. Based on the obtained results a patient record card model has been developed. The evaluation of its efficiency has been made. The patient record card model application allowed to unifytheranostic tactics to increase the part of conservatively treated patients to 57.5 %, to reduce the number of postoperative complications to 18.4 % and fatal outcomesto 2.5 %. It is performed that the videocolonoscopy at acute diverticulitis can be performed without increasing the risk of complications and 32.6 % is medical manipulation.

The study objective is analyzing the effects of atorvastatin loading dose on the reduction of myocardial infarction associated with percutaneous coronary interventions in patients with recanalization of chronic coronary artery occlusions. Between 2009 and 2015, 82 patients underwent recanalization. The main and control group included 38 patients who received a loading dose of atorvastatin (80 mg a day) before surgery, and 44 patients who were not administered the loading dose of atorvastatin. In both groups, troponin I and CF fraction of creatine phosphokinase were measured 1 day prior to surgery, 24 hours and 1 month after the percutaneous coronary intervention.

In the paper the clinical observation of a proliferating non-invasive grape mole and a suspected case for chorionepithelioma is presented. During the diagnostic procedure of the pathological process in a metra by express biopsy the trophoblastic neoplasia was suspected. In the postoperative period the diagnosis has been verified andnon-invasive grape moleconfirmed. Against the background of radical surgical treatment in the postoperative period the decrease of the very high level of chorionic gonadotropin in the blood with 986 826,0 mlU/ml to 5 640,0 55 U/L is marked.

In the paper the main stages of formation and development of type IV reactions are analyzed. The characteristics of some diseases, which have this type of reaction, is performed.

The socio-hygienic monitoring of the quality of nourishment of the Surgut city population, which indicates a significant deviation in the food pattern throughput the years, has been carried out. The overconsumption of foods with a high energy density, such as meat products, and the low level of consumption of dairy products, vegetables, fruits and fish, has been established. This dictates the need of a regional program development to ensure the rational nutrition of Khanty-Mansi Autonomous Okrug residents.

The study focuses on the determination of types of nonspecific adaptive reactions and the characteristics of metabolic indicators in physiological pregnancy with alien women residents of the Middle Ob region. A prospective study followed by a retrospective analysis of vegetative, haematological and biochemical values were conducted with 210 alien women of the subarctic region (Middle Ob region) with physiological pregnancy. It was registered that the women of the Middle Ob region have features of the “metabolism of northern type” at the pregnancy stages: lower total protein and albumin levels, higher glycaemic levels than the women of the Cis-Urals, which are most pronounced in the third trimester. The revealed features reflect the stages of the adaptation process, depending on the duration of residence in high latitude conditions.

The goal of the research is to evaluate features of uterine cervix non-neoplastic pathology and comorbide background at systematic undifferentiated connective tissue dysplasia. A comparative clinical and morphological analysis in patients with cervical pathology and the signs of systemic undifferentiated connective tissue dysplasia (group 1, n = 56) and without it (group 2, n = 39) has been carried out. The predominance of (67.8 %) stigmatization of the genitourinary system, particularly the obstetric-gynaecologic anamnesis - high frequency of infertility (26.8 % in group 2 and 7.7 %, p_1-2 = 0.0331), complications of pregnancy and delivery, disorders of menstrual function (39.3 %, p_1-2 = 0.0007), high frequency of hyperprolactinemia (42.8 %, p_1-2 = 0.0001), also epithelium dysplasia in transformation zone (66.0 %, group 2 - 12.8 %, p_1-2 = 0.0000), which are associated with different comorbide background, that probably forms the different nature of epigenomc effects in the presence and absence of connective tissue dysplasia and requires further study, are revealed.

The research of the pulmonary surfactant metabolism in male rats with repeated administration of dopamine into the lateral ventricle and systemic administration of haloperidol has been made. It has been established that the dysfunction of the dopaminergic system causes a decrement of the surface activity of the lining complex of the alveoles with multidirectional changes in the phospholipids of the surfactant. Cerebroventricular dopamine administration has been accompanied by an increase in phospholipids due to lysophosphatidylcholine, phosphatidylethanolamine and the selective blockade of D₂ receptors by the reduction of phospholipids, phosphatidylcholine and accumulation of lysophosphatidylcholine under conditions of the activation of phospholipase hydrolysis and the intensification of lipid acidification in lung tissue. The results indicate the formation of surfactantopathy in the imbalance of neurotransmission of dopamine.

The mutagenic properties of the RNA-containing drug RN-13 were studied in the gene mutation induction test (Ames test) on four strains of Salmonella typhimurium TA98, TA100, TA1535, TA1537. No statistically significant dose-dependent increase in the number of revertant colonies was observed for any strain of Salmonella typhimurium in the presence of the study drug in the studied range of doses from 4.0 to 40.0 mg/ml relative to the baseline level of spontaneous mutations. RNA-containing drug RN-13 in the studied dose range for strains TA98, TA100, TA1535, TA1537 Salmonella typhimurium does not have mutagenic activity.