The purpose of the study is to review the scientific literature on the evaluation of nutritional status and manifestations of malnutrition in children with cerebral palsy. Oropharyngeal dysfunction is one of the major factors defining difficulties during taking of food, leading to reduction of the consumed food and development of protein-energy malnutrition in patients with a cerebral palsy. The literature review presents modern approaches to the rehabilitation of patients. Considering the primary nutritional problem, comprehensive assessment of nutritional status of patient taking into account a dysphagia severity will allow to optimize enteral nutrition and to improve rehabilitation efficiency of children with a cerebral palsy.

The purpose of the study is to analyze data of major epidemiologic monitoring, registries and controlled clinical trials devoted to the problem of endovascular treatment of patients with chronic coronary occlusions. The successes, results, risks of these surgical procedures in relation to the type 4a myocardial infarction development in patients are discussed in detail in literature review.

Publications on joint cartilage structure damage diagnostics and treatment and their complications have been reviewed. In clinical practice local lesions of hyaline cartilages joint surface occur in 23-37% patients with destructive-dystrophic diseases, acting as the main pathology substrate. There are several therapies for joint cartilage diseases that can be divided into three groups: local stimulation, autotransplantation, transplantation of osteochondral transplants. Some methods of hyaline cartilage treatment are listed: debridement methods and surgical stimulation of proliferation of multipotent mesenchymal stromal cells of the bone marrow. The long-term results of these methods based on the functional state of knee joint were analyzed.

The aim of the study is to estimate the efficiency of various methods of arterial revascularization performed in terms of the angiosome theory concerning the dynamics of purulo-necrotic complications healing of different localization in patients with critical lower limb ischemia. In 67 patients with critical ischemia, angiosome-oriented intervention is accompanied by a decrease of stage necracetomies and small amputations in the soft tissue defect zone ( p < 0,05). The defect reparation rate in groups where revascularization was performed in terms of the angiosome theory tends to increase ( p > 0,05), repair of tissue defects of the arteria tibial anterior is faster. Transcutaneous oxymetry demonstrates parameters increase in the area of the injury during revascularization regardless of the mutilated angiosome localization and the applied principle of revascularization.

The aim of the study is to evaluate risk factors, possibilities of early diagnosis and operative treatment in very immature patients with spontaneous intestinal perforation in comparison with states of ileal dilatation preceding the perforation. A comparative analysis of the treatment results of 2 groups (14 and 12 very immature infants), who underwent spontaneous intestinal perforation and with the states preceding perforation is made. A special computer program for predicting a course of a disease and the choice of rational treatment is developed. As a result of the developed algorithm, the majority of patients (75 %; n = 9; p < 0.05) with conditions preceding ileal perforation were presented and operated at the early stage (2-3 days of life).

The aim of the paper is to determine the safety of prolonged antithrombotic therapy, the features of recanalization of the venous bed and the quality of life in patients with proximal deep vein thrombosis of lower limbs with prolonged use of warfarin, dabigatran etexilate and sulodexide for a year. In a prospective study, 186 patients with lancinating proximal thrombosis of deep veins were examined, divided into 3 groups, depending on the long-term antithrombotic therapy. It was found that the long-term use of dabigatran etexilate and sulodexide throghout the year is safer by 15.0 % and 17.0 % (p < 0.05) than the warfarin, and accompanied by the development of early recanalization and reduces the incidence of post-thrombotic syndrome .

Sarcoidosis morbidity is poorly studied in Russia. Clinical signs of sarcoidosis are diverse and lack of specific screening tests makes the non-invasive diagnostic procedures rather complicated. In general therapeutic practice diagnostics becomes rather complicated because of the necessity to differentiate the disease from other diseases with similar signs and symptoms in an atypical disease course. The clinical case described in the study confirms the complexity and specific features of sarcoidosis diagnostics at the Internal Diseases Department of a hospital.

The purpose of the study is to reveal the differences of food behavior in children of preschool age living in a city and a district (village), to enhance the effectiveness of preventive and therapeutic measures in patients with excessive body mass and obesity. A cross-sectional study with the continuous sampling method involving 311 children of preschool age living in the city and rural areas was conducted for determination of eating behavior features and their differences. The results showed that eating disorders with the risk of obesity are more common for children living in rural areas, despite the fact that the city has a lower incidence of obese children.

The purpose of the study is to identify drug procurement problems, and specifically for people suffering from diabetes mellitus, in particular, in the Khanty-Mansi Autonomous Okrug - Ugra. Application of a system analysis method allowed arranging the requirements of the federal act with regard to the drug procurement. A range of complications happening during the procurement is demonstrated. The analysis of the prevalence of diabetes mellitus showed a significant increase of this rate in recent years. A conclusion about the necessity of efficiency improvement of procurement procedures, including the need for permanent updating of the National registry databases of diabetes in Ugra.

The purpose of the study is to reveal possible diagnosis errors of enterovirus infection on a pre-hospital phase, to distinguish a course of enterovirus meningitis in children and adults. The retrospective analysis of 64 out-patient medical records with the final diagnosis of an enterovirus infection and also 57 in-patient medical records with the enterovirus meningitis diagnosis who was admitted to the infectious disease department of the Surgut Regional Clinical Hospital in 2016 was conducted. Results of a research reflect epidemiological, clinical and diagnostic features of the enterovirus infection among children and adults during the epidemic of 2015-2016 on the territory of the Surgut city.

The purpose of the study is to establish a dynamic pattern of hygiene indices and also features of a microbiocenosis of an oral cavity after an orthopedic treatment with removable dentures. Dental hygiene indices, a microbiocenosis of oral mucosa and a prosthesis surface in patients after an orthopedic treatment are defined. After prosthetics the average value of hygiene indices increased, as well as during the long-term use of removable dentures. Results of microbiology testing demonstrate the innidiation of dentures with bacteria that can make an adversely affect an oral health.

The purpose of this study is to study indicator values of clinical and laboratory methods for examining patients used to establish a diagnosis of acute opisthorchiasis and to identify the most significant indicators for detecting the disease at an early stage. Data for the study was 34 medical records of hospital patients who were treated in the infectious disease department of the Surgut Regional Clinical Hospital in 2017. The results of the studies revealed a wide range of variability in the values of diagnostic indicators, which differ significantly from the generally accepted ones used to establish a diagnosis at an early stage of the disease.

The purpose of the article is to analyze an anxiety level and quality of life of the third year students based on a value judgment of their health and living conditions. The survey was conducted with 143 Medical Institute students (97 girls and 46 boys). In students with different levels of anxiety were identified quantitative and qualitative differences of the quality of life indicators estimated by the questionnaire SF-36. The growth of anxiety is accompanied by the development of fatigue of the respondents and decrease of their vital activity. The emotional state, in which students are, limits their daily activities and reduces its quality. The decline of quality of life indicators is more pronounced in girls.

The aim of the study is to take an assessment of efficiency of skin oxygenation in applying external remedies (oxygen-containing emulsions) with the use of noninvasive methods of examination - a variation pulse oximetry with the optical sensor. Two groups of volunteers were examined. The 1st group consists of the fourth year students the Surgut State University at the age of 20-21 years (16 people). The 2nd group consists of the staff of the university aged 35-55 years (16 people). It was found out that in the 1st group the initial average rate of skin oxygenation was 97,0 ± 0,19, and 97,8 ± 0,20 after applying of an oxygen-containing emulsion. In the 2nd group the increase of blood oxygenation from 96,4 ± 0,17 to 97,9 ± 0,19 is noted. The obtained data offer the prospects of efficiency increase in phototherapy of patients with psoriasis and some chronic dermatosis.

The aim of the study is the determination of diagnostic significance of intestinal microbiocenosis state in prediction and prevention of changes in blood chemistry values. The lowering of blood chemistry values is established at different degrees of violation of instenial biocenosis. Such indices are the decrease in total protein, increase in relative levels of albumin, creatinine, urea, and cholesterol, triglycerides and low-density lipoproteins.

The article studies morphometric features of the epididymis under conditions of artificial immunosuppression. The study was carried out on 60 white rats of reproductive age. The state of immunosuppression was modeled by the use of cyclophosphamide intramuscularly in a dose of 1.5 mg/kg body weight for 10 days. Statistically significant decrease in the organometric parameters of the epididymis was detected both at the early (7, 15 days) and late observation periods (30 days), which are caused by intensive cumulation of immunosuppressive action. Changes at a microscopic level correlate in descent of macroscopic parameters, due to the effect of artificial immunosuppression on the synthetic apparatus of cells.

The purpose of the study is to establish morphofunctional changes in jejunum and ileum under influence of aluminum chloride on an animal organism. The experiment was carried out on 77 white outbred viripotent male rats with aluminum intoxication. Rats were divided into 5 groups according to the observation time. Under influence of aluminum chloride occur structural changes on walls of jejunum and ileum and all classes of immunoglobulin (A, M, G, E) show slow marker rising throughout the experiment.