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CORRELATION OF THE S100B PROTEIN AND THE DEGREE OF COGNITIVE IMPAIRMENTS IN PATIENTS WITH HIV INFECTION

https://doi.org/10.35266/2304-9448-2023-1-74-76

Abstract

The study aims to investigate the relation between cognitive impairments and neurospecific S100β protein in HIV patients. The quantitative content of the neurospecific S100β protein in the blood of 20 patients with HIV infection was determined using the Montreal scale (MoCa test). In all cases, HIV patients with cognitive impairment had an elevated level of S100β, while in some cases, patients with an increased level of the S100β protein did not suffer from cognitive decline. S100β may be a marker of central nervous system damage causing cognitive decline, but it is not clear whether elevated levels of S100β can be a predictor of future cognitive deficiency.

About the Authors

V. Z. Movsumov
Surgut State University, Surgut
Russian Federation

Lecturer, Neurologist
E-mail: veli.mov94@gmail.com



L. P. Smertina
Surgut State University, Surgut
Russian Federation

Candidate of Sciences (Medicine), Associate Professor, Neurologist

E-mail: Smertina@yandex.ru



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Review

For citations:


Movsumov V.Z., Smertina L.P. CORRELATION OF THE S100B PROTEIN AND THE DEGREE OF COGNITIVE IMPAIRMENTS IN PATIENTS WITH HIV INFECTION. Vestnik SurGU. Meditsina. 2023;16(1):74-76. (In Russ.) https://doi.org/10.35266/2304-9448-2023-1-74-76

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