MALIGNANCY INDEX (RMI) CALCULATION IN DIFFERENTIAL DIAGNOSTICS OF OVARIAN BORDERLINE AND MALIGNANT TUMORS
https://doi.org/10.1234/10.34822/2304-9448-2019-4-51-59
Abstract
The aim of the study is to evaluate the indicators of the malignancy index (RMI) in the differential diagnostics of benign, borderline and malignant ovarian tumors. Material and methods. The study includes 90 cases randomly selected from 746 cases using a random number generator. The cases are provided by the Oncology Unit of the Surgut Regional Clinical Hospital over the period 2008-2018. Patients with benign (30), borderline (30) and malignant (30) ovarian tumors are analyzed. Based on a comprehensive analysis, the calculation of the malignancy index (RMI) is performed. Results. The results evaluation of risk stratification of ovarian cancer, when calculating the prognostic RMI index in patients with borderline and malignant ovarian tumors, shows that the index has high prognostic value both in the period before menopause (p = 0.0000034) and in postmenopause (p = 0.0000041) and is an important method for the differential diagnostics of neoplastic ovarian pathology.
About the Authors
E. V. Logareva
Surgut State University
Russian Federation
Russian Federation
Postgraduate, Surgical Diseases Department, Medical Institute
e-mail: logareva@list.ru
A. E. Kasparova
Surgut State University
Russian Federation
Russian Federation
Doctor of Science (Medicine), Professor, Department of Pathophysiology and General Pathology, Medical Institute
anzkasparova@yandex.ru
A. M. Parsadanyan
Surgut State University
Russian Federation
Russian Federation
Doctor of Science (Medicine), Professor, Surgical Diseases Department, Medical Institute
e-mail: doctor_pars@mail.ru
References
1. Состояние онкологической помощи населению России в 2013 году : моногр. / под ред. А. Д. Ка- прина, В. В. Старинского, Г. В. Петровой. М. : ФГБУ МНИОИ им. П. А. Герцена Минздрава России, 2014. 235 с.
2. Katz V. L., Lentz G. M., Lobo R. A. Benign Gynecologic Lesions: Vulva, Vagina, Cervix, Uterus, Oviduct, Ovary // Comprehensive Gynecology. 5th ed. Philadelphia, PA: Mosby. 2007. Р 419-471.
3. Dutta S., Wang F. Q., Fleischer A. C., Fishman D. A. New Frontiers for Ovarian Cancer Risk Evaluation: Proteomics and Contrast-Enhanced Ultrasound // Am. J. Roentgenol. 2010. Vol. 194. P. 349-354.
4. Борисова Е. А., Пашов А. И., Буланов М. Н. Современное состояние проблемы дифференциальной диагностики опухолей яичников // Сиб. мед. обозрение. 2014. № 6. С. 14-19.
5. Manegold-Brauer G., Bellin A. K., Tercanli S., Lapaire O., Heinzelmann-Schwarz V. The Special Role of Ultrasound for Screening, Staging and Surveillance of Malignant Ovarian Tumors: Distinction from Other Methods of Diagnostic Imaging // Arch. Gynecol. Obstet. 2012. Vol. 289. P 491-498.
6. Timmerman D., Testa A. C., Bourne T., Ameye L., Jurkovic D., Van Holsbeke C. et al. Simple Ultrasound-Based Rules for the Diagnosis of Ovarian Cancer // Ultrasound Obstet Gynecol. 2008. No. 31 (6). Р 681-690.
7. Przybycin C. G., Kurman R. J., Ronnett B. M., Shih I. M., Vang R. Are All Pelvic (non Uterina) Serous Carcinomas of Tubal Origin? // Am. J. Surg. Pathol. 2010. Vol. 34. P 1407-1416.
8. Диагностика и лечение доброкачественных новообразований яичника с позиций профилактики рака : клинич. рек. (протокол лечения). М., 2018. 52 с.
9. Гаспаров А. С., Дубинская Е. Д., Паяниди Ю. Г., Бабичева И. А. Тактика ведения больных с кистозными образованиями яичников: прогнозирование (версии и контраверсии) // StatusPraesens. 2013. № 3 (14). С. 35-39.
10. Состояние онкологической помощи населению Ханты-Мансийского автономного округа - Югры в 2018 году (по данным годовых статистических отчетов, представленных учреждениями здравоохранения Ханты-Мансийского автономного округа - Югры). Ханты-Мансийск, 2019. 110 с.
Review
For citations:
Logareva E.V., Kasparova A.E., Parsadanyan A.M. MALIGNANCY INDEX (RMI) CALCULATION IN DIFFERENTIAL DIAGNOSTICS OF OVARIAN BORDERLINE AND MALIGNANT TUMORS. Vestnik SurGU. Meditsina. 2019;(4 (42)):51-59. (In Russ.) https://doi.org/10.1234/10.34822/2304-9448-2019-4-51-59
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