CLINICAL CASE OF GENERALIZED GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S DISEASE) IN ADOLESCENT AND THERAPY EFFICACY EVALUATION
https://doi.org/10.35266/2949-3447-2026-2-5
Abstract
The article aims to describe the pediatric challenges in treating patients having granulomatosis with polyangiitis (GPA) and emphasize the importance of using a multidisciplinary approach in managing multiple organ pathology of uncertain origin. To achieve this goal, the authors analyze a clinical case of generalized antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in a 16-year-old adolescent. The findings highlight the complexity and extended duration of a diagnostic search determined by polymorphic and gradually developing symptoms (damage to the ENT organs, joints, kidneys, and eyes). Therefore, the patient was found to have the specified disease after it had persisted for over a year. Delayed identification of the condition increases the risk of enduring organ damage, which could subsequently result in a poor prognosis despite an initial positive reaction to treatment. Thus, to improve the clinical outcomes of ANCA-associated vasculitis in teenagers, it is essential to raise awareness of the condition’s peculiarities among pediatricians.
About the Authors
T. М. Somova
Surgut State University, Surgut
Russian Federation
Russian Federation
Candidate of Sciences (Medicine), Docent, Pediatrician, Pediatric Cardiologist, Rheumatologist
A. A. Polovnikova
Surgut State University, Surgut
Russian Federation
Russian Federation
Resident, Pediatrician
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Review
For citations:
Somova T.М., Polovnikova A.A. CLINICAL CASE OF GENERALIZED GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S DISEASE) IN ADOLESCENT AND THERAPY EFFICACY EVALUATION. Vestnik SurGU. Meditsina. 2026;19(2):42-47. (In Russ.) https://doi.org/10.35266/2949-3447-2026-2-5
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