No 1 (35) (2018)
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EDITORIAL
CLINICAL MEDICINE. ORIGINAL RESEARCH
6-10 215
Abstract
The objective of the study is to determine indications and develop criteria for the best option of surgicaVl treatment of nonparasitic hepatic cysts. The analysis of treatment of 42 patients with nonparasitic hepatic cysts with the use of endovideosurgical method is presented. The results confirm that laparoscopic treatment of nonparasitic hepatic cysts is characterized by the least number of complications, low frequency of regressions and the absence of necessity for occasional surgical interventions. The use of external drainage of nonparasitic hepatic cysts controlled by imaging modality is preferable involving infectious complications of cysts. Open operations remain relevant in the presence of difficulties in differential diagnostics.
11-15 133
Abstract
The objective of the paper is to improve the differential diagnostics of acute appendicitis with the use of a transresonance functional topographer. A retrospective analysis was conducted involving 1,203 patients admitted in emergency to the surgical ward of the Saratov Military Medical Institute and the Emergency Hospital Number 1, Engels, from 2002 to 2017. The use of the transresonant functional topographer was included into overall tests for the purpose of establishing diagnoses. The magnitude of the radio-response at the projection level on the anterior abdominal wall L1 on the left, along the midclavicular line at suspicion on acute appendicitis greater than 6.01 V, indicates that there is no indication for appendectomy at the time of the test and requires further observation.
16-19 153
Abstract
The article describes the role of pathogenetic therapy of an alcoholinduced liver injury. The study included patients with alcoholic liver disease: 20 patients with chronic hepatitis and 10 patients with cirrhosis. The pathogenetic therapy with hepatoprotector liproxol was put on patients. Patients with chronic hepatitis showed a decrease in alanine transaminase activity by 1.7 times (p < 0.01), aspartate transaminase by 2.3 times (p < 0.01), an improvement in histological parameters of liver biopsy samples by a subsidence of piecemeal and bridging necrosis, intralobular dystrophy and focal necrosis and an inflammatory infiltration of the portal tracts became less significant, however, liver fibrosis persisted. Patients with alcoholic cirrhosis had a decrease in alanine transaminase by 1.5 times (p < 0.01), aspartate transaminase by 1.9 times (p < 0.05), and other indicators
CLINICAL MEDICINE. CLINICAL CASE
20-24 133
Abstract
The article describes a clinical case of left main bronchus rupture of a young woman sustaining a heavy concomitant injury, and new options of the pathology surgical treatment.
CLINICAL CASE OF SUCCESSFUL TREATMENT OF RECURRENT VARICOCELE IN MEN WITH THE MAY - THURNER SYNDROME
25-29 407
Abstract
The presented clinical case shows a new approach to the treatment of patients with chronic urological diseases. Data on the role of arteriovenous conflicts in the development of urological problems in men in the scientific medical literature are practically absent. The clinical case indicates that the May - Thurner syndrome may be the cause of a recurrent varicocele. The modern diagnostic algorithm in patients with varicocele is not aimed at detecting the May - Thurner syndrome and demonstrates the need to revise the indications for a surgical treatment of varicocele in patients with the syndrome.
30-32 586
Abstract
The paper describes an analysis of normative documents and a review of literature of the experience of electronic medical records realization of an outpatient. A discussion of advantages and disadvantages of this innovative accounting form as a review subject of medical care quality in a clinic is presented. Areas for improvement of this electronic document are indicated to improve the quality of medical care, to optimize and objectify its evaluation.
PREVENTIVE MEDICINE. REVIEWS
33-39 461
Abstract
The paper describes an analysis of normative documents and a review of literature of the experience of electronic medical records realization of an outpatient. A discussion of advantages and disadvantages of this innovative accounting form as a review subject of medical care quality in a clinic is presented. Areas for improvement of this electronic document are indicated to improve the quality of medical care, to optimize and objectify its evaluation
40-46 219
Abstract
He article presents the results of the questionnaire survey of pregnant women of the Surgut city on nutrition. The analysis of the relationship between the characteristics of eating behavior during pregnancy and risk of fetus macrosomia is conducted. The clinical aspects of the folic acid dosage are considered. The eating behavior of the half of interviewed pregnant women is impossible to declare desirable.
47-50 169
Abstract
The purpose of this study is to assess the level of anxiety in adolescents with different body mass. The study involved 290 students of secondary schools of Surgut. The Spielberger - Hanin test was used to evaluate the psychological phenomenon of anxiety. The degree of anxiety increased in frequency and intensity with the weight gain. The growth of anxiety in the group of patients was accompanied by various emotional disorders, which contributed to the increase of the body wight by reducing compliance to the treatment
51-55 442
Abstract
The object of the research is to study dynamics of main epidemiological indicators (prevalence and incidence) of diabetes in the Khanty-Mansi Autonomous Okrug - Ugra. Annual statistical reports “Disease incidence rate registered in patients living in the service area of a health facility” (form 12) and the depersonalized database of the state register of diabetes (requirements of Federal Law Number 152 “On Personal Data” of 27.07.2006) were used for the analysis. An increase in the prevalence of type 2 diabetes in the KhMAO - Ugra was registered with a decrease in the incidence. Constant updating of databases of the state register of diabetes provides monitoring of epidemiological indicants of the disease in the online mode, which is the basis for organization planning of medical and preventive care for the population.
56-63 222
Abstract
The object of the study is determined by the development of priority directions for prevention of cardiovascular pathology among representatives of indigenous small-numbered peoples of the North living in an urbanized environment By the method of Spearman’s rank correlation it is established that in representatives of the eastern subpopulation of the Khanty in urban conditions, elevated cholesterol levels and body mass index correlate with an increase in sympathetic activity. The directions of cardiovascular pathology prevention in representatives of indigenous small-numbered peoples of the North living in urbanized environment are suggested.
LIFE SCIENCES. ORIGINAL RESEARCH
64-68 238
Abstract
There were examined 100 pre-school children at the age of 4-6 to study the peculiarities of the regional mucosal immunity of the stomato- and nasopharynx among frequently ill children with the pathology of the tonsils and adenoids. The results of the study revealed changes in the parameters of the matrix metalloproteinases system and the saliva immunocytokine profile of patients with the pathology of the adenotonzillar system. These results make it possible to establish diagnostic indicants for the formation and course of an inflammatory process.
69-74 144
Abstract
The purpose of study work is to determine the leading ways of infection, the microbial spectrum of pathogens and morphological markers of placental structures in ascending, hematogenous and mixed contamination. During the morphological examination of placenta, 4 groups were marked out: without signs of infection of the placenta (n= 53), with ascending (n = 82), hematogenous (n = 40) and mixed infection (n = 49). It was revealed that structural changes in the placenta in all groups with intrauterine infection are involutional-dystrophic in nature. At the same time, compensatory reactions prevailed in the group without infection. The development of the inflammatory process in the placenta in ascending and mixed ways of infection was of a phasic nature, and reached in every third patient the maximum degree of infection - the infection of the umbilical cord.
75-84 194
Abstract
He article is devoted to a study of a component composition, as well as to an antioxidant and anti- inflammatory potential of northern berries in Western Siberia. The polyphenolic composition of bilberry, cranberry and lingonberry extracts from the northwestern regions of Western Siberia is determined. The highest concentration of polyphenol components was found in blueberry extracts. The antioxidant and anti-inflammatory potential, which depends on the concentration of polyphenols, was found through investigational studies in all extracts of northern berries.
85-89 156
Abstract
He purpose of the scientific study is to reveal mechanisms of the damaging effect of ionized iron in severe mechanical injury and to estimate efficiency of deferoxamine use to reduce the intensity of free-radical oxidation processes in the post-traumatic period. The experiments were carried out on 40 white Wistar male rats. The animals were injured in the middle third of the thigh on both sides with a preliminary injection of deferoxamine at a dose of 80 mg/kg in 5 ml of a 0.9 % NaCl solution into the abdominal cavity. In the blood serum contents of serum iron, transferrin and ferritin, spontaneous luminosity, rapid flare, light sum and latent stage of blood viscosity, low and medium molecular weight substances and oligopeptides were determined. It has been established that the use of deferoxamine in severe mechanical injuries accompanied by massive hemolysis of erythrocytes is promising and pathogenetically substantiated.
90-96 135
Abstract
The purpose of the study is to evaluate expression characteristics of the transforming growth factor beta and changes of the extracellular matrix in a stomach cancer associated with the undifferentiated connective tissue dysplasia. It is established that expression of the transforming growth factor beta in a tumor stroma in stomach cancer associated (1st group) and not-associated (2nd group) with the undifferentiated connective tissue dysplasia in both groups is higher in diffuse gastric cancer than in bowel type cancer. The bowel type cancer in the 1st group is structurally accompanied by a more pronounced degradation of the extracellular matrix. The accumulation of the transforming growth factor beta may indicate an unfavorable course of stomach cancer of the bowel type, as evidenced by frequent findings of a diffuse tumor component while examining the mucous membrane from all parts of an excised stomach
ISSN 2949-3447 (Online)