EXTRACELLULAR TRAPS: A NEW FUNCTION OF NEUTROPHILS AND THEIR ROLE IN INFLAMMATION AND HEMOSTASIS
https://doi.org/10.35266/2949-3447-2024-4-9
Abstract
The aim of the article is to review the scientific literature in PubMed and CyberLeninka databases with a search depth of 10 years using the following keywords: neutrophil extracellular traps, neutrophil granulocytes, platelets, inflammasome, coronavirus infection. Phagocytic activity of neutrophils, mechanisms of extracellular trap formation, their functions and roles in inflammation, connections with pathogenesis of hemostasis, roles of neutrophil traps in physiology, pathogenesis of diseases, infectious process in COVID-19 are discussed. The COVID-19 pandemic, along with new scientific evidence, has prompted a reevaluation of the link between inflammation and immune response, hemostasis and thrombosis. This reevaluation has highlighted neutrophils and their extracellular traps as crucial cells in this connection.
About the Authors
T. E. Kisina
North State Medical University, Arkhangelsk
Russian Federation
Russian Federation
Docent
N. A. Vorobyeva
North State Medical University, Arkhangelsk
Russian Federation
Russian Federation
Head of the Department
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Review
For citations:
Kisina T.E., Vorobyeva N.A. EXTRACELLULAR TRAPS: A NEW FUNCTION OF NEUTROPHILS AND THEIR ROLE IN INFLAMMATION AND HEMOSTASIS. Vestnik SurGU. Meditsina. 2024;17(4):63–74. (In Russ.) https://doi.org/10.35266/2949-3447-2024-4-9
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