ASSESSMENT OF FAT-SOLUBLE VITAMINS LEVELS IN PREGNANT WOMEN LIVING IN NORTHERN REGIONS
https://doi.org/10.35266/2949-3447-2024-4-6
Abstract
Increased formation of the reactive oxygen species leads to an increased risk of obstetric complications in the mother (pre-eсlampsia, gestational diabetes mellitus, miscarriage) and impaired fetus development. Researchers studied the dynamics of serum levels of fat-soluble vitamins A, E, and D in 53 pregnant women from the northern region at 10–12, 20–24, and 30–34 weeks of gestation. Twenty-three of them were overweight. The study revealed that the levels of vitamins A and E in all patients remained within reference values during pregnancy. At the same time, vitamin D in overweight women was within the deficit limits in I and II trimesters of pregnancy, increased to 30 ng/mL by the III trimester only in 17.4% and showed a significant statistical intergroup difference. Additional vitamin D supplementation before and during pregnancy, determination of its status at the stage of pregravidar preparation and, if necessary, monitoring during pregnancy can be attributed to preventive measures to reduce the risk of complications for the mother and newborn.
About the Authors
S. V. YakovenkoRussian Federation
Postgraduate, Dean
V. I. Korchin
Russian Federation
Doctor of Sciences (Medicine), Professor
E. A. Ugorelova
Russian Federation
Head of the Laboratory of Clinical Biochemistry and Immunology, Doctor of Clinical Laboratory Diagnostics
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Review
For citations:
Yakovenko S.V., Korchin V.I., Ugorelova E.A. ASSESSMENT OF FAT-SOLUBLE VITAMINS LEVELS IN PREGNANT WOMEN LIVING IN NORTHERN REGIONS. Vestnik SurGU. Meditsina. 2024;17(4):43-49. (In Russ.) https://doi.org/10.35266/2949-3447-2024-4-6