Preview

Vestnik SurGU. Meditsina

Advanced search

PROGRESSION MARKERS OF RENAL DYSFUNCTION BASED ON RESULTS OF CLINICAL AND MORPHOLOGICAL ANALYSIS IN PATIENTS WITH KIDNEY DISEASES

https://doi.org/10.35266/2949-3447-2024-3-5

Abstract

The analysis results are presented to determine the predictive relation between clinical and laboratory parameters of renal dysfunction and morphological changes in 70 patients with kidney diseases during the period 2019–2022. Researchers determined that hemodynamic changes, hyperazotemia, and age are critical factors in the progression of renal dysfunction and the development of nephrosclerosis in patients with kidney disease. The obtained regression models will allow predicting the formation of nephrosclerosis in patients with renal dysfunction in the absence of the possibility of morphological examination.

About the Authors

D. A. Vishnyak
Surgut State University, Surgut
Russian Federation

Candidate of Sciences (Medicine), Docent



A. Kh. Karimova
Surgut Regional Clinical Hospital, Surgut
Russian Federation

Nephrologist, Head of the Nephrology Department



V. R. Kofeeva
Surgut Regional Clinical Hospital, Surgut
Russian Federation

Nephrologist, Head of Local Nephrology Center



I. Yu. Dobrynina
Surgut State University; Surgut Regional Clinical Hospital, Surgut
Russian Federation

Doctor of Sciences (Medicine), Professor



R. T. Tovmasian
Surgut City Clinic No. 2, Surgut
Russian Federation

Nephrologist, Head of Inpatient Clinic



I. I. Zaytseva
Surgut Regional Clinical Hospital, Surgut
Russian Federation

Clinical Laboratory Diagnostician



A. M. Matveeva
Surgut State University, Surgut
Russian Federation

Candidate of Sciences (Medicine), Docent



L. A. Frolenkova
Surgut State University, Surgut
Russian Federation

Candidate of Sciences (Medicine), Docent



L. A. Naumova
Surgut State University, Surgut
Russian Federation

Doctor of Sciences (Medicine), Professor



References

1. Lv J.-C., Zhang L.-X. Prevalence and disease burden of chronic kidney disease // Advances in Experimental Medicine and Biology. 2019. No. 1165. P. 3–15. https://doi.org/10.1007/978-981-13-8871-2_1.

2. Андрусев А. М., Перегудова Н. Г., Шинкарев М. Б., Томилина Н. А. и др. Заместительная почечная терапия хронической болезни почек 5 стадии в Российской Федерации 2016-2020 гг. Краткий отчет по данным Общероссийского Регистра заместительной почечной терапии Российского диализного общества // Нефрология и диализ. 2022. Т. 24, № 4. С. 555–565.

3. Yamanouchi M., Hoshino J., Ubara Y. et al. Clinicopathological predictors for progression of chronic kidney disease in nephrosclerosis: a biopsy-based cohort study // Nephrology Dialysis Transplantation. 2019. Vol. 34, no. 7. P. 1182–1188. https://doi.org/10.1093/ndt/gfy121.

4. Jha V., Garcia-Garcia G., Iseki K. et al. Chronic kidney disease: global dimension and perspectives // The Lancet 2013. No. 382. P. 260–272. https://doi.org/10.1016/S0140-6736(13)60687-X.

5. Saran R., Robinson B., Abbott K. C. US Renal Data System 2016 Annual Data Report: Epidemiology of kidney disease in the United States // American Journal of Kidney Diseases. 2017, Vol. 69, no. 3. P. A7–A8. https://doi.org/10.1053/j.ajkd.2016.12.004.

6. ERA-EDTA Registry: Annual report 2015. URL: https://www.eraonline.org/wp-content/uploads/2022/11/ERA-Registry-Annual-Report-2015.pdf (дата обращения: 15.11.2024).

7. Masakane I., Nakai Sh., Ogata S. Annual Dialysis Data Report 2014, JSDT Renal Data Registry (JRDR) // Renal Replacement Therapy. 2017. No. 3. P. 18. https://doi.org/10.1186/s41100-017-0097-8.

8. Liang S., Le W., Liang D. et al. Clinico-pathological characteristics and outcomes of patients with biopsy-proven hypertensive nephrosclerosis: a retrospective cohort study // BMC Nephrology. 2016. No. 17. P. 42. https://doi.org/10.1186/s12882-016-0254-2.

9. Haruhara K., Tsuboi N., Kanzaki G. et al. Glomerular density in biopsy-proven hypertensive nephrosclerosis // American Journal of Hypertension. 2015. Vol. 28, no. 9. P. 1164–1171. https://doi.org/10.1093/ajh/hpu267.

10. Morduchowicz G., Boner G., Ben-Bassat M. et al. Proteinuria in benign nephrosclerosis // Archives of Internal Medicine. 1986. Vol. 146, no. 8. P. 1513–1516. https://doi.org/10.1001/ archinte.1986.00360200063011.

11. Narvarte J., Privé M., Saba S. R. et al. Proteinuria in hypertension // American Journal of Kidney Diseases. 1987. No. 10. P. 408–416. https://doi.org/10.1016/s0272-6386(87)80186-5.

12. Toto R. D. Proteinuria and hypertensive nephrosclerosis in African Americans // Kidney International Supplements. 2004. Vol. 66, no. S92. P. S102–S104. https://doi.org/10.1111/j.1523-1755.2004.09224.x.

13. Dasgupta I., Porter C., Innes A. et al. “Benign” hypertensive nephrosclerosis // QJM: An International Journal of Medicine. 2007. Vol. 100, no. 2. P. 113–119. https://doi.org/10.1093/qjmed/hcl139.

14. Vikse B. E., Aasarød K., Bostad L. et al. Clinical prognostic factors in biopsy-proven benign nephrosclerosis // Nephrology Dialysis Transplantation. 2003 Vol. 18, no. 3. P. 517–523. https://doi.org/10.1093/ndt/18.3.517.

15. Sumida K., Hoshino J., Ueno T. et al. Effect of proteinuria and glomerular filtration rate on renal outcome in patients with biopsy-proven benign nephrosclerosis // PLoS One. 2016. Vol. 11, no. 1. P. e0147690. https://doi.org/10.1371/journal.pone.0147690.

16. Momoki K., Kataoka H., Moriyama T. et al. Hyperuricemia as a predictive marker for progression of nephrosclerosis: Clinical assessment of prognostic factors in biopsy-proven arterial/arteriolar nephrosclerosis // Journal Atherosclerosis and Thrombosis. 2017. Vol. 24, no. 6. P. 630–642. https://doi.org/10.5551/jat.37523.

17. Furuichi K., Shimizu M., Yuzawa Y. et al. Nationwide multicenter kidney biopsy study of Japanese patients with hypertensive nephrosclerosis // Clinical Experimental Nephrology. 2018. Vol. 22, no. 3. P. 629–637. https://doi.org/10.1007/s10157-017-1496-4.

18. Вишняк Д. А., Каримова А. Х., Кофеева В. Р. и др. Опыт проведения и диагностическая значимость пункционной нефробиопсии в стационаре регионального уровня // Вестник СурГУ. Медицина. 2024. Т. 17, № 1. С. 40–48. https://doi.org/10.35266/2949-3447-2024-1-5.

19. Хроническая болезнь почек: клинические рекомендации. 2024. URL: https://rusnephrology.org/wp-content/uploads/2024/06/КР_ХБП_от_10.06.2024.pdf (дата обращения: 01.11.2024).

20. Острое повреждение почек: проекты клинических рекомендаций РФ. URL: https://rusnephrology.org/professional/gudlines/(дата обращения: 01.11.2024).

21. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney International // Kidney International. 2024. Vol. 105, no. 4. P. S117–S314. https://doi.org/10.1016/j.kint.2023.10.018.

22. Левицкая Е. С., Батюшин М. М., Чистяков В. А. и др. Ремоделирование артерий почек малого диаметра в прогнозе прогрессирования тубулоинтерстициального фиброза при хроническом гломерулонефрите // Кардиоваскулярная терапия и профилактика. 2019. Т. 18, № 3, С. 62–68.

23. Вишняк Д. А., Мехралыева Н. П., Каримова А. Х. и др. Пункционная нефробиопсия и ее клинико-диагностическое значение на примере опыта Сургутской окружной клинической больницы // Терапия. 2023. Т. 9, № S3. С. 101–102.

24. Sumida K., Takeda A., Furuichi K. et al. Clinicopathological discordance in biopsy-proven nephrosclerosis: A nationwide cross-sectional study of the Japan Renal Biopsy Registry (J-RBR) // Clinical and Experimental Nephrology. 2021. Vol. 26, no. 4. P. 325–332. https://doi.org/10.1007/s10157-021-02161-1.

25. Razzaque M. S., Azouz A., Shinagawa T. et al. Factors regulating the progression of hypertensive nephrosclerosis // Contributions to Nephrology. 2003. Vol. 139. P. 173–186. https://doi.org/10.1159/000071743.

26. Кузьмич М. М., Мехралыева Н. П. Определение предикторов нефросклероза у пациентов с заболеваниями почек // XIX Международная (XXVIII Всероссийская) Пироговская науч. мед. конф. студентов и молодых ученых : сб. тез., 21 марта 2024 г., г. Москва. М. : РНИМУ им. Н. И. Пирогова, 2024. С. 53.


Review

For citations:


Vishnyak D.A., Karimova A.Kh., Kofeeva V.R., Dobrynina I.Yu., Tovmasian R.T., Zaytseva I.I., Matveeva A.M., Frolenkova L.A., Naumova L.A. PROGRESSION MARKERS OF RENAL DYSFUNCTION BASED ON RESULTS OF CLINICAL AND MORPHOLOGICAL ANALYSIS IN PATIENTS WITH KIDNEY DISEASES. Vestnik SurGU. Meditsina. 2024;17(4):35-42. (In Russ.) https://doi.org/10.35266/2949-3447-2024-3-5

Views: 141


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2949-3447 (Online)