IMMUNOMODULATORY EFFECTS OF VITAMIN D AND NOVEL CORONAVIRUS DISEASE
https://doi.org/10.34822/2304-9448-2021-2-71-76
Abstract
The study aims to review the current evidence of the effects of vitamin D on immunity and coronavirus disease 2019 (COVID-19). Material and methods. The analysis of scientific literature sources in the databases PubMed,
eLIBRARY.RU, etc. is made. The keywords used are vitamin D, immunity, and COVID-19. Results. Vitamin D affects innate cellular and acquired immunity. Its immunomodulatory effect is associated with the activation of antiviral
activity, the influence on the differentiation of T-lymphocytes, and a decrease in the synthesis of pro-inflammatory cytokines. Research confirms a clear link between low vitamin D levels and a range of infectious diseases, including
severity and mortality from the COVID-19. One of the promising areas in the prevention and treatment of COVID-19 can be the administration of vitamin D, which supports antiviral immunity and reduces the effects of the cytokine
storm.
About the Authors
I. P. Kushnikova
Surgut State University, Surgut
Russian Federation
Russian Federation
Candidate of Sciences (Medicine), Associate Professor, Internal Diseases Department, Medical Institute
Е-mail: ira222052@mail.ru
N. V. Nelidova
Surgut State University, Surgut
Russian Federation
Russian Federation
Candidate of Sciences (Medicine), Associate Professor, Multidisciplinary Clinical Education Department, Medical Institute
Е-mail: nelidovanv80@mail.ru
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Review
For citations:
Kushnikova I.P., Nelidova N.V. IMMUNOMODULATORY EFFECTS OF VITAMIN D AND NOVEL CORONAVIRUS DISEASE. Vestnik SurGU. Meditsina. 2021;(2 (48)):71-76. (In Russ.) https://doi.org/10.34822/2304-9448-2021-2-71-76
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