FEATURES OF PATIENTS’ PROFILE WITH ACUTE BLEEDING FROM THE UPPER GASTROINTESTINAL TRACT
https://doi.org/10.34822/2304-9448-2021-2-22-29
Abstract
The study aims to investigate the patients’ profile with acute bleeding from the upper gastrointestinal tract. Material and methods. The causes of upper gastrointestinal bleeding in 1,299 patients treated in Nizhnevartovsk Regional Clinical Hospital, Khanty-Mansi Autonomous Okrug – Ugra, Russia, during 2018–2020 are analyzed. Results. Тhis pathology accounted for 18.5% of the total number of patients with acute surgical pathology who were admitted urgently to a surgical unit. The average age of the patients was 53 ± 14.3 years, and 72.3% of those hospitalized are men. It was found that the proportion of peptic ulcer bleeding reaches 48.7%, less often the causes of bleeding are erosive lesions of the gastrointestinal mucosa (27.6%), Mallory–Weiss syndrome (8.3%), esophageal and gastric varices (7,6%), neoplasia (6.7%), angiodysplasia (1.1%). In 33.7% of patients with primary esophagogastroduodenoscopy, prolonged bleeding was revealed. Preliminary gastric lavage and sedation made it possible to increase the information content of primary esophagogastroduodenoscopy to 93.7%.
About the Authors
V. V. DarvinRussian Federation
Doctor of Sciences (Medicine), Professor, Head, Surgical Diseases Department, Medical Institute
Е-mail: dvv@mf.surgu.ru
A. Ya. Ilkanich
Russian Federation
Doctor of Sciences (Medicine), Docent, Professor of the Surgical Diseases Department, Medical Institute
Е-mail: ailkanich@yandex.ru
A. V. Satinov
Russian Federation
Chief Medical Officer, Surgeon
M. G. Ryzhikov
Russian Federation
Endoscopist, Head, Endoscopy Department
Е-mail: orcchief@yandex.ru
A. V. Oganian
Russian Federation
Endoscopist
Endoscopist, Nizhnevartovsk Regional Clinical Hospital, Nizhnevartovsk, Russia; Postgraduate, Surgical Diseases Department, Medical Institute
Е-mail: niak1994@mail.ru
A. N. Bryukhov
Russian Federation
Candidate of Sciences (Medicine), Deputy Chief Medical Officer for Temporary Incapacity to Work Expertize, Anaesthesiologist-reanimatologist
Е-mail: bannv1@yandex.ru
P. N. Kolmakov
Russian Federation
Candidate of Sciences (Medicine), Docent, Endoscopist
References
1. Nelms D. W., Pelaez C. A. The Acute Upper Gastrointestinal Bleed // Surg Clin North Am. 2018. Vol. 98, № 5. P. 1047–1057. DOI 10.1016/j.suc.2018.05.004.2018.
2. Moledina S. M., Komba E. Risk Factors for Mortality among Patients Admitted with Upper Gastrointestinal Bleeding at a Tertiary Hospital: A Prospective Cohort Study // BMC Gastroenterology. 2017. Vol. 17, № 1. P. 165.
3. Patel V., Nicastro J. Upper Gastrointestinal Bleeding // Clinics in Colon and Rectal Surgery. 2019. Vol. 33, № 1. P. 42–44.
4. Stanley A. J., Laine L. Management of Acute Upper Gastrointestinal Bleeding // BMJ. 2019. Vol. 364, P. 1536.
5. Rosenstock S. J., Møller M. H., Larsson H. et al. Improving Quality of Care in Peptic Ulcer Bleeding: Nationwide Cohort Study of 13,498 Consecutive Patients in the Danish Clinical Register of Emergency Surgery // American Journal of Gastroenterology. 2013. Vol. 108, № 9. P. 1449–1457.
6. Hearnshaw S. A., Logan R. F., Lowe D. et al. Acute Upper Gastrointestinal Bleeding in the UK: Patient Characteristics, Diagnoses and Outcomes in the 2007 UK Audit // Gut. 2011. Vol. 60, № 10. P. 1327–1335.
7. Miilunpohja S., Jyrkkä J., Kärkkäinen J. M. et al. Long-term Mortality and Causes of Death in Endoscopically Verified Upper Gastrointestinal Bleeding: Comparison of Bleeding Patients and Population Controls // Scandinavian Journal of Gastroenterology. 2017. Vol. 52, № 11. P. 1211–1218.
8. El-Tawil A. M. Trends on Gastrointestinal Bleeding and Mortality: Where are We Standing? // WJG. 2012. Vol. 18, № 11. P. 1154.
9. Tayyem O., Bilal M., Samuel R., Merwat S. K. Evaluation and Management of Variceal Bleeding // Disease-a-Month. 2018. Vol. 64, № 7. P. 312–320.
10. Haq I., Tripathi D. Recent Advances in the Management of Variceal Bleeding // Gastroenterology Report. 2017. Vol. 5,№ 2. P. 113–126.
11. Гостищев В. К., Евсеев М. А. Гастродуоденальные кровотечения язвенной этиологии. М. : ГЭОТАР-Медиа, 2008. 397 с.
12. Targownik L. E., Nabalamba A. Trends in Management and Outcomes of Acute Nonvariceal Upper Gastrointestinal Bleeding: 1993–2003 // Clinical Gastroenterology and Hepatology. 2006. Vol. 4, № 12. P. 1459–1466.
13. Тимен Л. Я., Трубицина И. Е., Чикунова Б. З. и др. Геморрагический шок. Особенности эндоскопического гемостаза при язвенных гастродуоденальных кровотечениях: патоморфологическое, экспериментальное и клиническое исследование // Medical consultation. 2003. Т. 39, № 2. С. 3–19.
14. Гостищев В. К., Евсеев М. А. Эндоскопический гемостаз и прогнозирование рецидивной геморрагии при острых гастродуоденальных язвенных кровотечениях // Гастродуоденальные кровотечения язвенной этиологии : руководство. 2008. С. 129–175.
15. Панцырев Ю. М., Михалев А. И., Федоров Е. Д. Хирургическое лечение прободных и кровоточащих гастродуоденальных язв // Хирургия. 2003. № 3. С. 43–49.
16. Сацукевич В. Н., Сацукевич Д. В. Острые желудочно-кишечные кровотечения из хронических гастродуоденальных язв // Кремлевская медицина. 2000. Т. 2. С. 49–53.
17. Короткевич А. Г., Антонов Ю. А., Лобыкин Ф. И. и др. Сравнительная оценка эндоскопического гемостаза при состоявшемся язвенном кровотечении // Эндоскопическая хирургия. 2004. № 4. С. 41–44.
18. Ogasawara N., Mizuno M., Masui R. et al. Predictive Factors for Intractability to Endoscopic Hemostasis in the Treatment of Bleeding Gastroduodenal Peptic Ulcers in Japanese Patients // Clinical Endoscopy. 2014. Vol. 47, № 2. P. 162.
19. Sung J. Current Management of Peptic Ulcer Bleeding // Nature Clinical Practice Gastroenterology & Hepatology. 2006. Vol. 3, № 1. P. 24–32.
20. Вербицкий В. Г. Желудочно-кишечные кровотечения язвенной этиологии (патогенез, диагностика, лечение) : дис. … д-ра мед. наук. СПб., 1999. 309 с.
21. Barkun A. N., Almadi M., Kuipers E. J. et al. Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations from the International Consensus Group // Annals of Internal Medicine. 2019. Vol. 171, № 11. Р. 805–822.
22. Samuel R., Bilal M., Tayyem O., Guturu P. Evaluation and Management of Non-Variceal Upper Gastrointestinal Bleeding //Disease-a-Month. 2018. Vol. 64, № 7. Р. 333–343.
23. Mohammad S., Chandio B., Shaikh A., Soomro A. A., Rizwan A. Endoscopic Findings in Patients Presenting with Upper Gastrointestinal Bleeding // Cureus. 2019. Vol. 11, № 3.
24. Danış N., Tekin F., Akarca U. S. et al. Changing patterns of Upper Gastrointestinal Bleeding Over 23 Years in Turkey // The Turkish Journal of Gastroenterology. 2019. Vol. 30, № 10. Р. 877.
25. Zaltman C., Souza H. S., Castro M. E. et al. Upper Gastrointestinal Bleeding in a Brazilian Hospital: A Retrospective Study of Endoscopic Records // Arquivos de Gastroenterología. 2002. Т. 39, №. 2. Р. 74–80.
26. Steinfeld B., Scott J., Vilander G. et al. The Role of Lean Process Improvement in Implementation of Evidence-Based Practices in Behavioral Health Care // The Journal of Behavioral Health Services & Research. 2015. Vol. 42, № 4. Р. 504–518.
27. Язвенные гастродуоденальные кровотечения: клинич. рекомендации. URL: https://www.mrckb.ru/files/ yazvennye_gastroduodenalnye_krovotecheniya.PDF (дата обращения: 25.04.2021).
28. Субботин А. М., Кузин М. Н., Ефимова Е. И., Мухин А. С. Стандартизация эндоскопической терминологии. Оформление протокола диагностической эзофагогаст-родуоденоскопии и колоноскопии (на основе МСТ 3.0 гастроинтестинальной эндоскопии). Нижний Новгород, 2016. 112 с.
Review
For citations:
Darvin V.V., Ilkanich A.Ya., Satinov A.V., Ryzhikov M.G., Oganian A.V., Bryukhov A.N., Kolmakov P.N. FEATURES OF PATIENTS’ PROFILE WITH ACUTE BLEEDING FROM THE UPPER GASTROINTESTINAL TRACT. Vestnik SurGU. Meditsina. 2021;(2 (48)):22-29. (In Russ.) https://doi.org/10.34822/2304-9448-2021-2-22-29