PLATELET-RICH PLASMA: TECHNOLOGY, MECHANISM OF ACTION IN ANDROGENETIC ALOPECIA
https://doi.org/10.34822/2304-9448-2020-3-62-68
Abstract
The study aims to present literature data on the technology and effectiveness of the use of platelet-rich
plasma in hair transplantation. Material and methods. We studied the publications of foreign authors, reviews of randomized controlled trials from various sources of scientific literature, including the PubMed platform. The keywords used are hair loss, androgenetic alopecia, hair transplantation, platelet-rich plasma, PRP therapy. Results. The mechanism of action of the PRP therapy in androgenic alopecia is a complex multi-stage process involving growth factors and suppression of apoptosis. This method is not a substitute for hair transplantation but can shorten the treatment time, improve the quality of grafts, and provide a better result after hair transplantation considering the adherence to standard recommendations and possible synergistic effects in combination therapy for hair loss.
plasma in hair transplantation. Material and methods. We studied the publications of foreign authors, reviews of randomized controlled trials from various sources of scientific literature, including the PubMed platform. The keywords used are hair loss, androgenetic alopecia, hair transplantation, platelet-rich plasma, PRP therapy. Results. The mechanism of action of the PRP therapy in androgenic alopecia is a complex multi-stage process involving growth factors and suppression of apoptosis. This method is not a substitute for hair transplantation but can shorten the treatment time, improve the quality of grafts, and provide a better result after hair transplantation considering the adherence to standard recommendations and possible synergistic effects in combination therapy for hair loss.
About the Authors
A. F. Khalirakhmanov
Uniclinic KFU, Kazan,
Kazan (Volga Region) Federal University, Kazan
Russian Federation
Candidate of Sciences (Medicine), Physician in Endovascular Diagnostics and Treatment,
Russian Federation
Candidate of Sciences (Medicine), Physician in Endovascular Diagnostics and Treatment,
Senior Lecturer, Department of Surgery, Obstetrics, and Gynecology
Е-mail: ai.bolit@mail.ru
K. F. Idrisova
Uniclinic KFU, Kazan,
Kazan (Volga Region) Federal University, Kazan
Russian Federation
Russian Federation
Clinical Research Assistant;
Е-mail: idrisovakam@mail.ru
A. R. Abdrakhmanov
Uniclinic KFU, Kazan,
Kazan (Volga Region) Federal University, Kazan
Russian Federation
Russian Federation
Candidate of Sciences (Medicine), Dermatovenerologist, Head, Therapeutic Department, Deputy Chief Medical Officer for Treatment, Researcher
Е-mail: dr.abdrakhmanov.azat@yandex.ru
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Review
For citations:
Khalirakhmanov A.F., Idrisova K.F., Abdrakhmanov A.R. PLATELET-RICH PLASMA: TECHNOLOGY, MECHANISM OF ACTION IN ANDROGENETIC ALOPECIA. Vestnik SurGU. Meditsina. 2020;(3 (45)):62-68. https://doi.org/10.34822/2304-9448-2020-3-62-68
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