EXPERIMENTAL RATIONALE OF EARLY ENTERAL NUTRITION IN BOWEL RESECTION
https://doi.org/10.1234/10.34822/2304-9448-2019-4-94-101
Abstract
The aim of the study is to conduct a comprehensive analysis of the effect of early enteral nutrition on the postsurgery dynamics of clinical, laboratory, functional and morphological parameters in experimental animals with the operated small intestine. Material and methods. An experimental study is conducted on 20 male Chinchilla rabbits. During the study, the outcomes of early enteral nutrition compared with parenteral in resection of the small intestine are studied based on the assessment of laboratory and functional parameters, as well as the morphological pattern of the healing of small intestinal anastomoses. The study is conducted in compliance with all the International Recommendations of the European Convention for the Protection of Vertebrate Animals Used for Experimental and other Scientific Purposes. Results. The results allow concluding that the conducted early enteral nutrition contributes to the quick recovery of protein and energy metabolism, accelerates the normalization of the function of the gastrointestinal tract and epithelialization processes in the anastomosis zone.
About the Authors
E. A. Krasnov
Surgut State University; Surgut Regional Clinical Hospital
Russian Federation
Russian Federation
PhD (Medicine), Associate Professor, Surgical Diseases Department, Medical Institute
Deputy Chief Medical Officer on Surgical Service
e-mail: 86krasnovartem@mail.ru
V. V. Darvin
Surgut State University
Russian Federation
Russian Federation
Doctor of Science (Medicine), Professor, Head, Surgical Diseases Department, Medical Institute
e-mail: e.suhojckova2012@yandex.ru
A. N. Varganova
Surgut State University; Surgut Regional Clinical Hospital
Russian Federation
Russian Federation
Postgraduate, Surgical Diseases Department, Medical Institute
Head, Clinical Pharmacology Unit
e-mail: Alexvarg24@yandex.ru
E. V. Bubovich
Surgut State University
Russian Federation
Russian Federation
PhD (Medicine), Assistant Professor, Department of Pathophysiology and General Pathology, Medical Institute
e-mail: bubvichev@gmail.com
N. V. Klimova
Surgut State University; Surgut Regional Clinical Hospital
Russian Federation
Russian Federation
Doctor of Science (Medicine), Professor, Head, Multiprofile Clinic Training Department, Medical Institute
Head, Department of Radiology
e-mail: knv@mail.ru
V. E. Viduto
Surgut Regional Clinical Hospital
Russian Federation
Russian Federation
Forensic Pathologist
e-mail: Ikar-malikova@ya.ru
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Review
For citations:
Krasnov E.A., Darvin V.V., Varganova A.N., Bubovich E.V., Klimova N.V., Viduto V.E. EXPERIMENTAL RATIONALE OF EARLY ENTERAL NUTRITION IN BOWEL RESECTION. Vestnik SurGU. Meditsina. 2019;(4 (42)):94-101. (In Russ.) https://doi.org/10.1234/10.34822/2304-9448-2019-4-94-101
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