MICROSCOPIC AND SUBMICROSCOPIC CHANGES IN KIDNEYS DURING ORGANISM ADAPTATION TO CELLULAR DEHYDRATION
Abstract
The aim of the study is to evaluate cellular dehydration in different degrees of severity, the nature of the structural changes in the nephron and the specific features of the dynamics of reparative processes during the recovery period in experimental conditions.
Materials and methods. The study is performed on 112 young white rats-males (Wistar line) with an initial weight of 115–120 g. The rats are divided into 2 groups: intact and adapted to dehydration.
Results. Histological and morphometric studies established a relationship between the duration of the dehydrating factor and the depth of damage to the structures of the filtration and reabsorption barriers. After severe cellular dehydration, reparative processes occur slowly and do not lead to the full normalization of nephron structures.
About the Authors
L. Ya. Fedonyuk
I. Horbachevsky Ternopil State Medical University
Ukraine
Ukraine
O Yu. Loboda
Kiev Clinical Hospital No 2 of Railway Service
Ukraine
Ukraine
V. O. Khavtur
I. Horbachevsky Ternopil State Medical University
Ukraine
Ukraine
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Review
For citations:
Fedonyuk L.Ya., Loboda O.Yu., Khavtur V.O. MICROSCOPIC AND SUBMICROSCOPIC CHANGES IN KIDNEYS DURING ORGANISM ADAPTATION TO CELLULAR DEHYDRATION. Vestnik SurGU. Meditsina. 2019;(1 (39)):90-96. (In Russ.)
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