THE PHENOMENON OF CYSTOGENESIS AS A POSSIBLE MARKER OF EPITHELIAL-STROMAL RELATION DISORDER
Abstract
The study objective is the investigation of cyctogensis occurrence rate in chronic gastric mucosa disorders. Clinical study data have been analyzed; morphological examination of gastric biopsy specimens and surgery tissues taken from patients with chronic atrophic gastritis (CAG, Group 1) and gastric cancer (GC, Group 2) have been performed and associated with systemic undifferentiated connective tissue dysplasia (CTD); the control group has included patients with the same disorder but with no CTD signs (Group 3 and 4). It is shown that cyctoenesis in various organs occurs only in CTD patients (Group 1 and 2) with a statistically significant difference from the control groups. In the GC groups it is associated with a higher intestinal metaplasia and dysplasia occurrence rate. It leads to the conclusion that cyctogenesis can be considered as one of markers or the primary epithelial-stromal relation disorder phenotype.
About the Authors
L. A. Naumova
Surgut State University
Russian Federation
Russian Federation
O. N. Osipova
Surgut Regional Clinical Hospital
Russian Federation
Russian Federation
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Review
For citations:
Naumova L.A., Osipova O.N. THE PHENOMENON OF CYSTOGENESIS AS A POSSIBLE MARKER OF EPITHELIAL-STROMAL RELATION DISORDER. Vestnik SurGU. Meditsina. 2017;(1 (31)):62-67. (In Russ.)
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