MODERN POSSIBILITIES OF BRONCHIAL ASTHMA PREDICTION IN CHILDREN
https://doi.org/10.35266/2304-9448-2023-3-15-23
Abstract
The study aims to generalize data on the topic of methods for risk stratification of bronchial asthma in children, preliminary with wheezing, obtained from domestic and foreign literature from PubMed and eLIBRARY.RU. The search depth was 25 years. The study compared numerous predictive models, such as traditional clinical and laboratory scoring systems and high-technology monomarkers of a disease, with an emphasis on the most informative prospective examinations. The theoretical potential and practical results of studying protein in the extracellular matrix of periostin and laminin were analyzed as forecast markers of bronchial asthma in children.
Keywords
About the Authors
V. P. GaponenkoRussian Federation
Assistant Professor, Postgraduate
E-mail: v.p.gaponenko@yandex.ru
E. E. Shlykova
Russian Federation
Deputy Chief Medical Officer in Medical Field
E-mail: 55@gdkb2-omsk.ru
References
1. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2022. 223 p. URL: https://ginasthma.org/wp-content/uploads/2022/07/GINA-Main-Report-2022-FINAL-22-07-01-WMS.pdf (дата обращения: 21.04.2023).
2. Most Recent National Asthma Data. URL: https://www.cdc.gov/asth/most_recent_national_asthma_data.htm (дата обращения:21.04.2023).
3. Mallol J., García-Marcos L., Solé D. et al. International prevalence of recurrent wheezing during the first year of life: Variability, treatment patterns and use of health resources. Thorax. 2010;65(11):1004–1009.
4. Геппе Н. А., Колосова Н. Г. Бронхиальная обструкция у детей дошкольного возраста // Consilium Medicum. 2016. Т. 18, № 11. С. 25–29.
5. Mozun R., Ardura-Garcia C., Pedersen E. S. L. et al. Agreement of parent-and child-reported wheeze and its association with measurable asthma traits. Pediatr Pulmonol. 2021;56(12):3813–3821.
6. Davis K. J., Disantostefano R., Peden D. B. Is Johnny wheezing? Parentchild agreement in the Childhood Asthma in America survey. Pediatr Allergy Immunol. 2011;22(1 Pt 1):31–35.
7. Lo D., Danvers L., Roland D. et al. Misdiagnosis of children’s asthma is common in UK primary care and can be improved with objective tests. European Respiratory Journal. 2018;52(suppl 62):PA1314.
8. Yang C. L., Simons E., Foty R. G. et al. Misdiagnosis of asthma in schoolchildren. Pediatr Pulmonol. 2017;52(3):293–302.
9. Looijmans-van den Akker I., van Luijn K., Verheij T. Overdiagnosis of asthma in children in primary care: A retrospective analysis. Br J Gen Pract. 2016;66(644):e152–e157.
10. Kavanagh J., Jackson D. J., Kent B. D. Over- and under-diagnosis in asthma. Breathe (Sheff). 2019;15(1):e20–e27.
11. Castro-Rodríguez J. A., Holberg C. J., Wright A. L. et al. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med. 2000;162(4 Pt 1):1403–1406.
12. Chang T. S., Lemanske R. F. Jr, Guilbert T. W. et al. Evaluation of the modified asthma predictive index in high-risk preschool children. J Allergy Clin Immunol Pract. 2013;1(2):152–156.
13. Amin P., Levin L., Epstein T. et al. Optimum predictors of childhood asthma: Persistent wheeze or the Asthma Predictive Index? J Allergy Clin Immunol Pract. 2014;2(6):709–715.
14. Kurukulaaratchy R. J., Matthews S., Holgate S. T. et al. Predicting persistent disease among children who wheeze during early life. Eur Respir J. 2003;22(5):767–771.
15. Caudri D., Wijga A., A. Schipper C. M. et al. Predicting the long-term prognosis of children with symptoms suggestive of asthma at preschool age. J Allergy Clin Immunol. 2009;124(5):903–910.e7.
16. Pescatore A. M., Dogaru C. M., Duembgen L. et al. A simple asthma prediction tool for preschool children with wheeze or cough. J Allergy Clin Immunol. 2014;133(1):111–118.e13.
17. Шахова Н. В., Камалтынова Е. М., Кашинская Т. С. и др. Предикторы развития бронхиальной астмы у детей дошкольного возраста с рекуррентным бронхообструктивным синдромом // Российский вестник перинатологии и педитарии. 2021. Т. 66, № 3. С. 70–76. DOI 10.21508/1027-4065-2021-66-3-70-76.
18. Савенкова Н. Д. Прогноз риска развития бронхиальной астмы у детей с бронхообструктивным синдромом : автореф. дис. … канд. мед. наук. Астрахань, 2020. 24 с.
19. Самигуллина Н. В. Совершенствование диагностики бронхиальной астмы у детей на амбулаторном этапе : автореф. дис. … канд. мед. наук. М., 2019. 24 с.
20. Мизерницкий Ю. Л., Павленко В. А., Мельникова И. М. Клинико-функциональные критерии прогноза бронхиальной астмы в раннем детском возрасте // Российский вестник перинатологии и педиатрии. 2015. Т. 60, № 4. С. 82–88.
21. Kreißl S., Hendler S., Akmatov M. K. et al. Reduced exhaled breath condensate pH and severity of allergic sensitization predict school age asthma. J Allergy Clin Immunol Pract. 2021;9(4):1570–1577.
22. Guo J., Zhu W., Wang H. et al. Risk factors and prognosis of recurrent wheezing in Chinese young children: A prospective cohort study. Allergy Asthma Clin Immunol. 2019;15:38.
23. Wang R., Simpson A., Custovic A. et al. Individual risk assessment tool for school-age asthma prediction in UK birth cohort. Clin Exp Allergy. 2019;49(3):292–298.
24. Bonato M., Bazzan E., Snijders D. et al. Clinical and pathologic factors predicting future asthma in wheezing children. A longitudinal study. Am J Respir Cell Mol Biol. 2018;59(4):458–466.
25. Zhang Y., Zhou C., Liu J. et al. A new index to identify risk of multi-trigger wheezing in infants with first episode of wheezing. J Asthma. 2014;51(10):1043–1048.
26. Vial Dupuy A., Amat F., Pereira B. et al. A simple tool to identify infants at high risk of mild to severe childhood asthma: The persistent asthma predictive score. J Asthma. 2011;48(10):1015–1021.
27. Amat F., Vial A., Pereira B. et al. Predicting the long-term course of asthma in wheezing infants is still a challenge. ISRN Allergy. 2011;2011:493624.
28. Matricardi P. M., Illi S., Grüber C. et al. Wheezing in childhood: Incidence, longitudinal patterns and factors predicting persistence. Eur Respir J. 2008;32(3):585–592.
29. Sherriff A., Peters T. J., Henderson J. et al. Risk factor associations with wheezing patterns in children followed longitudinally from birth to 3(1/2) years. Int J Epidemiol. 2001;30(6):1473–1484.
30. Li J., Tiwari A., Mirzakhani H. et al. Circulating MicroRNA: Incident Asthma prediction and vitamin D effect modification. J Pers Med. 2021;11(4):307.
31. Katayama S., Stenberg Hammar K., Krjutškov K. et al. Acute wheeze-specific gene module shows correlation with vitamin D and asthma medication. Eur Respir J. 2020;55(1):1901330.
32. Hyvärinen M. K., Kotaniemi-Syrjänen A., Reijonen T. M. et al. Eosinophil activity in infants hospitalized for wheezing and risk of persistent childhood asthma. Pediatr Allergy Immunol. 2010;21(1 Pt 1): 96–103.
33. Reubsaet L. L., Meerding J., de Jager W. et al. Plasma chemokines in early wheezers predict the development of allergic asthma. Am J Respir Crit Care Med. 2013;188(8):1039–1040.
34. Smolinska A., Klaassen E. M., Dallinga J. W. et al. Profiling of volatile organic compounds in exhaled breath as a strategy to find early predictive signatures of asthma in children. PLoS One. 2014;9(4):e95668.
35. Carraro S., Bozzetto S., Giordano G. et al. Wheezing preschool children with early-onset asthma reveal a specific metabolomic profile. Pediatr Allergy Immunol. 2018;29(4):375–382.
36. Singer F., Luchsinger I., Inci D. et al. Exhaled nitric oxide in symptomatic children at preschool age predicts later asthma. Allergy. 2013;68(4):531–538.
37. Li J., Wu J., Liu H. et al. A pilot study to evaluate the role of circulation CD4 + CCR6 + CRTh2 + cell in predicting risk of asthma in wheezing children. BMC Pediatr. 2021;21(1):263.
38. Kim C. K., Kim J. T., Kang H. et al. Sputum eosinophilia in cough-variant asthma as a predictor of the subsequent development of classic asthma. Clin Exp Allergy. 2003;33(10):1409–1414.
39. Caudri D., Wijga A. H., Hoekstra M. O. et al. Prediction of asthma in symptomatic preschool children using exhaled nitric oxide, Rint and specific IgE. Thorax. 2010;65(9):801–807.
40. Shores D. R., Everett A. D. Children as Biomarker Orphans: Progress in the field of pediatric biomarkers. J Pediatr. 2018;193:14–20.e31.
41. Соботюк Н. В., Гапоненко В. П., Бочанцев С. В. и др. Потенциальная роль сывороточного периостина в ранней диагностике бронхиальной астмы у детей // Вопросы современной педиатрии. 2016. Т. 15, № 5. С. 452–456. DOI 10.15690/vsp.v15i5.1619.
42. Шахова Н. В. Периостин – биомаркер бронхиальной астмы // Вопросы современной педиатрии. 2019. Т. 18, № 5. С. 339–345. DOI 10.15690/vsp.v18i5.2056.
43. Kii I., Ito H. Periostin and its interacting proteins in the construction of extracellular architectures. Cell Mol Life Sci. 2017;74(23):4269–4277.
44. Barbato A., Turato G., Baraldo S. et al. Epithelial damage and angiogenesis in the airways of children with asthma. Am J Respir Crit Care Med. 2006;174(9):975–981.
45. Saglani S., Payne D. N., Zhu J. et al. Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers. Am J Respir Crit Care Med. 2007;176(9):858–864.
46. Berankova K., Uhlik J., Honkova L. et al. Structural changes in the bronchial mucosa of young children at risk of developing asthma. Pediatr Allergy Immunol. 2014;25(2):136–142.
47. Christie P. E., Jonas M., Tsai C. H. et al. Increase in laminin expression in allergic airway remodelling and decrease by dexamethasone. Eur Respir J. 2004;24(1):107–115.
48. Blanchard C., Mingler M. K., McBride M. et al. Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunol. 2008;1(4):289–296.
49. Sehra S., Yao W., Nguyen E. T. et al. Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol. 2011;186(8):4959–4966.
50. Song J. S., You J. S., Jeong S. I. et al. Serum periostin levels correlate with airway hyper-responsiveness to methacholine and mannitol in children with asthma. Allergy. 2015;70(6):674–681.
51. Guvenir H., Buyuktiryaki B., Kulhas Celik I. et al. Can serum periostin, YKL-40, and osteopontin levels in pre-school children with recurrent wheezing predict later development of asthma? Pediatr Allergy Immunol. 2021;32(1):77–85.
52. Anderson H. M., Lemanske R. F. Jr, Arron J. R. et al. Relationships among aeroallergen sensitization, peripheral blood eosinophils, and periostin in pediatric asthma development. J Allergy Clin Immunol. 2017;139(3):790–796.
53. Amin K., Janson C., Sevéus L. et al. Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics. Respir Res. 2005;6(1):110.
54. Prabhala P., Wright D. B., Robbe P. et al. Laminin α4 contributes to airway remodeling and inflammation in asthma. Am J Physiol Lung Cell Mol Physiol. 2019;317(6):L768–L777.
Review
For citations:
Gaponenko V.P., Shlykova E.E. MODERN POSSIBILITIES OF BRONCHIAL ASTHMA PREDICTION IN CHILDREN. Vestnik SurGU. Meditsina. 2023;16(3):15-23. (In Russ.) https://doi.org/10.35266/2304-9448-2023-3-15-23