EVALUATION OF THE EFFECT OF PLANT POLYPHENOLS AND FLAVONOIDS ON THE COURSE OF PREGNANCY AND ITS OUTCOMES
https://doi.org/10.1234/10.34822/2304-9448-2021-1-67-74
Abstract
The study aims to analyze the contemporary scientific literature on the influence of polyphenols and flavonoids on the course of pregnancy and its outcomes. Material and methods. In the course of the work, literature was
searched in the MEDLINE, PubMed, eLIBRARY.RU, and RSCI databases through the following keywords: polyphenols, flavonoids, preeclampsia, placental insufficiency, intrauterine growth restriction. The analysis of 120 publications was carried out. As a result, 41 literature sources were selected. The search depth was ten years. Results. Analysis of the information currently available indicates a large gap in the knowledge regarding the safety of these compounds for reproductive processes. Thus, it is necessary to conduct additional studies of the safety profile of active polyphenolic compounds in experimental conditions and it is essential to monitor the data on the situation in clinical practice.
About the Authors
L. V. Kovalenko
Surgut State University, Surgut
Russian Federation
Russian Federation
Doctor of Sciences (Medicine), Professor, Head, Department of Pathophysiology and General Pathology, Professor of the Department of Pathophysiology and General Pathology, Director, Medical Institute
E-mail: lvkhome@yandex.ru
L. D. Belotserkovtseva
Surgut State University;
Surgut Regional Clinical Prenatal Centre, Surgut
Russian Federation
Russian Federation
Doctor of Sciences (Medicine), Professor, Head, Department of Obstetrics, Gynecology and Perinatology, Medical Institute;
Chief Medical Officer
Е-mail: info@surgut-kpc.ru
A. E. Kasparova
Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk;
Surgut State University, Surgut
Е-mail: anzkasparova@yandex.ru
Russian Federation
Russian Federation
Doctor of Sciences (Medicine), Professor, Head, Department of Obstetrics and Gynecology, Vice-Rector for Training Highly Qualified Personnel and Additional Professional Education;
Professor of the Department of Pathophysiology and General Pathology, Medical Institute
Е-mail: anzkasparova@yandex.ru
I. I. Mordovina
Surgut State University, Surgut
Russian Federation
Russian Federation
Candidate of Sciences (Medicine), Associate Professor, Department of Obstetrics, Gynecology and Perinatology, Medical Institute
Е-mail: mar-mariot@yandex.ru
A. E. Gulyaev
National Center for Biotechnology, Nur-Sultan,
Kazakhstan
Kazakhstan
Doctor of Sciences (Medicine), Professor, Scientific Consultant
Е-mail: akin@mail.ru
N. S. Kavushevskaya
Surgut State University, Surgut
Russian Federation
Russian Federation
Candidate of Sciences (Biology), Associate Professor, Department of Pathophysiology and General Pathology
T. A. Sinyukova
Surgut State University, Surgut
Russian Federation
Russian Federation
Researcher, Research and Educational Center, Medical Institute
E-mail: proles@bk.ru
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Review
For citations:
Kovalenko L.V., Belotserkovtseva L.D., Kasparova A.E., Mordovina I.I., Gulyaev A.E., Kavushevskaya N.S., Sinyukova T.A. EVALUATION OF THE EFFECT OF PLANT POLYPHENOLS AND FLAVONOIDS ON THE COURSE OF PREGNANCY AND ITS OUTCOMES. Vestnik SurGU. Meditsina. 2021;(1 (47)):67-74. (In Russ.) https://doi.org/10.1234/10.34822/2304-9448-2021-1-67-74
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