CHEST CT SCAN FOR COVID-19-RELATED PNEUMONIA IN PATIENTS WITH CHRONIC RENAL FAILURE

The study aims to evaluate the signs and extent of lung damage in patients with pneumonia affected by COVID-19, associated with end-stage renal disease (ERSD) and without kidney disease, according to the data of computed tomography (CT) of the chest organs. Material and methods. The group of patients with pneumonia and ERSD had 53 people and the group without kidney disease consisted of 59 people. Despite the appropriate
treatment, all patients died. The autopsy confirmed the presence of pneumonia caused by COVID-19. The average age of the patients was 68.40 ± 14.63 years. All 112 patients had chest CT 2.12 ± 0.94 days before death. Results. The lethal outcome in patients with pneumonia caused by COVID-19 and long-term ESRD occurred when the extent of the lung damage equaled 40.64 ± 18.50% with fluctuations from 3 to 69%. Among the patients without
kidney disease, the extent of lung damage was 56.63 ± 19.17%, (p < 0.05) with fluctuations from 18 to 94%. According to CT data the ground-glass opacification, crazy-paving, and consolidation signs were observed in 100.0% of patients in both groups. These signs were referred to as the main ones for the purposes of the study. The frequency of other signs such as air bronchogram, pleural thickening, pleurisy, lymphadenopathy, atelectasis, local emphysema, nodules, reticulation, calcifications, fibrosis, bronchiectasis, and pulmonary edema ranged from 2 to 73%. There was no statistically significant difference in the frequency of the signs in both groups. The most frequent locations of pneumonia were the lower (94.4%) and posterior (98.2%) parts of the lungs, regardless of the group observed. The percentage of the severity of the main signs in the lungs was significantly lower among the patients with long-term ERSD.

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