CLINICAL AND INSTRUMENTAL INDICATORS OF VASCULAR COMORBIDITY IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS

The aim of the study is to identify comorbidity characteristics in patients with multifocal atherosclerosis taking into account the heterogeneity of clinical symptomatology for estimation of disease topography and prevention.

Materials and Methods. According to the hierarchical analysis of categorical variables patients are divided up into 3 clusters: cluster 1 (96 patients) – clinical manifestations of atherosclerotic cardiovascular disease; cluster 2 (96 patients) – cerebral atherosclerosis; cluster 3 (96 patients) – lower extremity arterial disease. The diseases are proved at coronary angiography, Doppler ultrasonography of the major artery of the head and lower extremities. Clinical state, electrocardiogram, and echocardiogram in all patients are evaluated.

Results. Patients of the cluster 1 are diagnosed with a predominance of stage 3 arterial hypertension and stenosis > 30 % in the left internal carotid artery territory. Hemodynamically significant stenosis in the right common carotid artery territory, atherosclerotic plaques in the right and left common carotid arteries are dominant among patients of the cluster 3.

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