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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgumed</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник СурГУ. Медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Vestnik SurGU. Meditsina</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-3447</issn><publisher><publisher-name>Сургутский государственный университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35266/2949-3447-2024-1-2</article-id><article-id custom-type="elpub" pub-id-type="custom">surgumed-722</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА. ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE. REVIEWS</subject></subj-group></article-categories><title-group><article-title>ИСТОРИЯ И ЭВОЛЮЦИЯ МЕТОДОВ НЕЙРОВИЗУАЛИЗАЦИИ В ЭПИЛЕПТОЛОГИИ</article-title><trans-title-group xml:lang="en"><trans-title>HISTORY AND EVOLUTION OF NEUROIMAGING METHODS IN EPILEPTOLOGY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-7409-0957</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельников</surname><given-names>Александр Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikov</surname><given-names>Aleksandr A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач-рентгенолог, врач-радиолог</p></bio><bio xml:lang="en"><p>Candidate of Sciences (Medicine), X-Ray Therapist, Radiologist</p></bio><email xlink:type="simple">alexradiology@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4589-6528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климова</surname><given-names>Наталья Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Klimova</surname><given-names>Natalya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующая рентгенологическим отделением</p></bio><bio xml:lang="en"><p>Doctor of Sciences (Medicine), Professor, Head of the Radiology Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1111-6378</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронкова</surname><given-names>Кира Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Voronkova</surname><given-names>Kira V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор</p></bio><bio xml:lang="en"><p>Doctor of Sciences (Medicine), Professor</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научный центр хирургии имени академика Б. В. Петровского, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Petrovsky B. V. Russian Scientific Center for Surgery, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Сургутский государственный университет, Сургут;&#13;
Сургутская окружная клиническая больница, Сургут</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University, Surgut;&#13;
Surgut District Clinical Hospital, Surgut</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет имени Н. И. Пирогова&#13;
Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>05</month><year>2024</year></pub-date><volume>17</volume><issue>1</issue><fpage>21</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мельников А.А., Климова Н.В., Воронкова К.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Мельников А.А., Климова Н.В., Воронкова К.В.</copyright-holder><copyright-holder xml:lang="en">Melnikov A.A., Klimova N.V., Voronkova K.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgumed.ru/jour/article/view/722">https://www.surgumed.ru/jour/article/view/722</self-uri><abstract><p>Рассмотрена история фундаментальных открытий, методов и клинических достижений в области нейровизуализации, их вклад в развитие диагностики, лечения и понимания этиологии эпилепсии, в том числе в рамках исследований Международной Противоэпилептической Лиги (International League Against Epilepsy, ILAE). На первых этапах своего становления нейровизуализация бурно развивалась в направлении расширения возможностей краниографии, пневмоэнцефалографии, пневмомиелографии, вентрикулографии, линейной томографии и селективной ангиографии. Большое влияние на развитие эпилептологии оказало использование методов компьютерной и магнитно-резонансной томографии, позволивших выявить патологические поражения у большого числа пациентов с криптогенной эпилепсией, расширить показания к хирургическому лечению и улучшить понимание патогенеза патологических процессов в головном мозге, связанных с судорожной активностью. В последние годы в центре внимания исследователей оказалась функциональная магнитно-резонансная томография, магнитно-резонансная спектроскопия, позитронно-эмиссионная томография и однофотонная эмиссионная компьютерная томография, позволившие выявить огромное количество различных структурных изменений мозговой ткани, лежащих в основе формирования эпилептического очага и приводящих к развитию фокальной эпилепсии.</p></abstract><trans-abstract xml:lang="en"><p>The article examines history of fundamental discoveries, methods and clinical achievements in neuroimaging, their contribution to the development of diagnosing, treatment and understanding of epilepsy etiology, also as part of International League Against Epilepsy’s research. In the early stages of its development, neuroimaging had advanced rapidly in the areas of cancer detection, pneumoencephalography, pneumomiography, ventriculography, linear tomography and selective angiography. The development of epileptology was greatly influenced by the use of computed tomography and magnetic resonance imaging, which made it possible to identify pathological lesions in a large number of patients with cryptogenic epilepsy, expand the indications for surgical treatment and improve understanding of the pathogenesis of pathological processes in the brain associated with seizure activity. In recent years, functional magnetic resonance imaging, magnetic resonance spectroscopy, positron emission tomography and single-photon emission computed tomography have become the focus of attention of researchers, which revealed a huge number of different structural changes of the brain tissue, which lie at the basis of the formation of the epileptic focus and lead to the development of focal epilepsy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>история рентгенологии</kwd><kwd>нейровизуализация</kwd><kwd>эпилепсия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>radiology history</kwd><kwd>neuroimaging</kwd><kwd>epilepsy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Неврология : нац. руководство / под ред. Е. И. Гусева, А. Н. Коновалова, В. И. Скворцовой, А. Б. Гехт. Т. 1. 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