surgumedВестник СурГУ. МедицинаVestnik SurGU. Meditsina2949-3447Сургутский государственный университет10.35266/2304-9448-2023-3-75-82surgumed-684Research ArticleМЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИ. ОБЗОР ЛИТЕРАТУРЫLIFE SCIENCES. REVIEWSЭТИОЛОГИЯ ВНЕБОЛЬНИЧНОЙ ПНЕВМОНИИ У ДЕТЕЙ ДО И ПОСЛЕ НАЧАЛА ЭПОХИ КОНЪЮГИРОВАННЫХ ВАКЦИНETIOLOGY OF COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN BEFORE AND AFTER AN ERA OF CONJUGATE VACCINEShttps://orcid.org/0000-0003-3653-3696УглеваТ. Н.UglevaT. N.

доктор медицинских наук, доцент

E-mail: tatjana.ugleva@yandex.ru

Doctor of Sciences (Medicine), DocentE-mail:  tatjana.ugleva@yandex.ru

https://orcid.org/0000-0003-3452-5975УшаковаО. Н.UshakovaO. N.

участковый врач-педиатр, аспирант

E-mail: ushakova.doc@mail.ru

District Pediatrician, Postgraduate

E-mail: ushakova.doc@mail.ru

Ханты-Мансийская государственная медицинская академия, Ханты-МансийскРоссияKhanty-Mansi State Medical Academy, Khanty-MansiyskRussian FederationОкружная клиническая больница, Ханты-МансийскРоссияDistrict Clinical Hospital, Khanty-MansiyskRussian Federation2023290920231637582Copyright © Углева Т.Н., Ушакова О.Н., 20232023Углева Т.Н., Ушакова О.Н.Ugleva T.N., Ushakova O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.surgumed.ru/jour/article/view/684

Цель – анализ изменения этиологии внебольничной пневмонии у детей до и после начала применения конъюгированных вакцин против Streptococcus pneumoniae и Haemophilus influenzae типа b для выработки диагностических стратегий и эмпирических методов лечения. Проведен обзор опубликованных данных научной литературы в базах данных PubMed, Web of Science и РИНЦ о демографических показателях, особенностях спектра возбудителей внебольничной пневмонии у детей до и после глобального внедрения конъюгированных вакцин во многих странах. Введение плановой вакцинации детей против Streptococcus pneumoniae и против Haemophilus influenzae типа b резко сократило заболеваемость и тяжесть внебольничной пневмонии у детей. Существенно снизилась доля типичных бактериальных возбудителей и возросла доля вирусов и атипичных бактерий (Mycoplasma pneumoniae) в этиологии внебольничной пневмонии у детей.

The study aims to analyze changes in the etiology of community-acquired pneumonia in children before and after use of conjugate vaccinations against Streptococcus pneumoniae and Haemophilus influenzae type b in order to develop diagnostic strategies and empirical methods of treatment. The scientific literature on demographic indicators and the trigger profile of community-acquired pneumonia in children before and after massive use of conjugate vaccines in many countries was searched for in PubMed, Web of Science, and RISC and reviewed. Routine Streptococcus pneumoniae and Haemophilus influenzae type b vaccination rapidly lowered the morbidity and severity of community-acquired pneumonia in children. There was a dramatic decline in common bacterial triggers and an increase in viruses and atypical bacteria (Mycoplasma pneumoniae) in the etiology of community-acquired pneumonia in children.

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The authors declare that there are no conflicts of interest present.