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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgumed</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник СурГУ. Медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Vestnik SurGU. Meditsina</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-3447</issn><publisher><publisher-name>Сургутский государственный университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35266/2304-9448-2023-2-34-44</article-id><article-id custom-type="elpub" pub-id-type="custom">surgumed-653</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА. ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE. ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>ФАКТОРЫ РИСКА, ОСОБЕННОСТИ ТЕЧЕНИЯ БЕРЕМЕННОСТИ И ИСХОДЫ У ПАЦИЕНТОК С РАННЕЙ ПРЕЭКЛАМПСИЕЙ ПРИ МНОГОПЛОДНОЙ И ОДНОПЛОДНОЙ БЕРЕМЕННОСТИ</article-title><trans-title-group xml:lang="en"><trans-title>RISK FACTORS FOR AND FEATURES OF MULTIPLE AND SINGLETON PREGNANCY COURSE AND OUTCOMES IN PATIENTS WITH EARLY PREECLAMPSIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4396-4606</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудринских</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudrinskikh</surname><given-names>I A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>преподаватель, врач-акушер-гинеколог</p><p>E-mail: irischka-kudrs@mail.ru</p></bio><bio xml:lang="en"><p>Lecturer, Obstetrician-Gynaecologist</p><p>E-mail: irischka-kudrs@mail.ru</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6995-4863</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоцерковцева</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Belotserkovtseva</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор</p><p>E-mail: info@surgut-kpc.ru</p></bio><bio xml:lang="en"><p>Doctor of Sciences (Medicine), Professor</p><p>E-mail: info@surgut-kpc.ru</p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4415-7897</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мордовина</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mordovina</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент</p><p>E-mail: mordovina_ii@surgu.ru</p></bio><bio xml:lang="en"><p>Candidate of Sciences (Medicine), Docent</p><p>E-mail: mordovina_ii@surgu.ru</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сургутский государственный университет, Сургут;&#13;
Сургутский окружной клинический центр охраны материнства и детства, Сургут</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University, Surgut;&#13;
Surgut District Clinical Center for Maternal and Child Health, Surgut</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Сургутский государственный университет, Сургут</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University, Surgut</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2023</year></pub-date><volume>16</volume><issue>2</issue><fpage>34</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кудринских И.А., Белоцерковцева Л.Д., Мордовина И.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Кудринских И.А., Белоцерковцева Л.Д., Мордовина И.И.</copyright-holder><copyright-holder xml:lang="en">Kudrinskikh I.A., Belotserkovtseva L.D., Mordovina I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgumed.ru/jour/article/view/653">https://www.surgumed.ru/jour/article/view/653</self-uri><abstract><p>Цель – оценка факторов риска осложненного течения беременностей по ретроспективному анализу 510 историй болезни за период 2014–2021 гг. и случаев родоразрешения в Сургутском окружном клиническом центре охраны материнства и детства с многоплодной и одноплодной беременностью, осложненной и неосложненной ранней преэклампсией. Установлено, что развитию преэклампсии при одноплодной беременности могут способствовать хроническая артериальная гипертензия, избыточная масса тела, гипотиреоз,преэклампсия в анамнезе, а ее манифестация сопровождается худшими неонатальными исходами и более выраженными проявлениями полиорганной недостаточности. При многоплодной беременности значимым фактором риска преэклампсии явилось использование вспомогательных репродуктивных технологий, но течение патологического процесса протекало в виде умеренных форм ранней преэклампсии и не было сопряжено с неблагоприятными перинатальными исходами.</p></abstract><trans-abstract xml:lang="en"><p>The study aims to evaluate risk factors for complicated pregnancy courses based on the retrospective analysis of 510 anamneses from 2014 to 2021, as well as singleton and multiple pregnancies outcomes with and without preeclampsia registered in the Surgut District Clinical Center for Maternal and Child Health. The study states that chronic arterial hypertension, obesity, hypothyroidism, and preeclampsia in anamnesis may result in preeclampsia in singleton pregnancy, while its manifestation is associated with the worst neonatal outcomes and a more apparent multiple organ dysfunction syndrome. In multiple pregnancy, assisted reproductive techniqueswere a significant risk factor for preeclampsia. However, the pathological process demonstrated a moderate type of early preeclampsia and was not associated with unfavorable perinatal outcomes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>преэклампсия</kwd><kwd>многоплодная беременность</kwd><kwd>гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>preeclampsia</kwd><kwd>multiple pregnancy</kwd><kwd>hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Krotz S., Fajardo J., Ghandi S. et al. 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