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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgumed</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник СурГУ. Медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Vestnik SurGU. Meditsina</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-3447</issn><publisher><publisher-name>Сургутский государственный университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">surgumed-204</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИ. ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LIFE SCIENCES. REVIEWS</subject></subj-group></article-categories><title-group><article-title>ПОТЕНЦИАЛ ГЕРОПРОТЕКТОРНОЙ АКТИВНОСТИ ПОЛИФЕНОЛОВ ТИПИЧНЫХ СЕВЕРНЫХ ЯГОД</article-title><trans-title-group xml:lang="en"><trans-title>THE POTENTIAL OF GEROPROTECTIVE ACTIVITY IN POLYPHENOLS TYPICAL OF NORTHERN BERRIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривых</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivykh</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент, заведующая кафедрой общественного здоровья и здравоохранения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуляев</surname><given-names>А. Е</given-names></name><name name-style="western" xml:lang="en"><surname>Gulyaev</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, г. Астана, Республика Казахстан</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваленко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalenko</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующая кафедрой патофизиологии и общей патологии, директор медицинского института</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ханты-Мансийская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Khanty-Mansiysk State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Частное Учреждение «National Laboratory Astana» Назарбаев Университет</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>“National Laboratory Astana”, Nazarbayev University</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сургутский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>05</month><year>2019</year></pub-date><volume>0</volume><issue>1 (39)</issue><fpage>65</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кривых Е.А., Гуляев А.Е., Коваленко Л.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кривых Е.А., Гуляев А.Е., Коваленко Л.В.</copyright-holder><copyright-holder xml:lang="en">Krivykh E.A., Gulyaev A.E., Kovalenko L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgumed.ru/jour/article/view/204">https://www.surgumed.ru/jour/article/view/204</self-uri><abstract><p>Цель – представить аналитический материал о потенциале геропротекторной активности полифенолов северных ягод: клюквы, брусники, черники. </p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен литературный поиск в базах PubMed за последние 7 лет. Использованы ключевые слова: антивозрастной эффект (anti-aging), полифенолы, геропротекторы, клюква, брусника, черника, антиоксиданты, метаболический синдром и др.</p></sec><sec><title>Результаты</title><p>Результаты. Результаты ряда экспериментальных работ и имеющиеся ограниченные клинические доказательства позволяют предполагать, что полифенолы северных ягод способны оказывать связанные с антиоксидативным действием некоторые потенциально терапевтические anti-aging эффекты при возраст-ассоциированной патологии. Исследования anti-aging эффектов северных ягод Западной Сибири и полифенольных экстрактов этих ягод представляются актуальными и необходимыми.</p></sec></abstract><trans-abstract xml:lang="en"><p>The aim of the study is to present the analysis findings of the geroprotective activity potential polyphenols of the Northern berries such as cranberries, lingonberries and blueberries. </p><sec><title>Materials and methods</title><p>Materials and methods. The review of the literature in the base PubMed over the past 7 years is made. The used keywords are: anti-aging effect, polyphenols, geroprotectors, cranberries, lingonberries, blueberries, antioxidants, metabolic syndrome and others.</p></sec><sec><title>Results</title><p>Results. The results of several experiments and known limited clinical evidence allow considering that polyphenols of the Northern berries can have antioxidant activity with possible anti-aging effect regarding aging pathology. The study of antiaging effects of the Northern berries in Western Siberia and their polyphenols is important and essential.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>патологическое старение</kwd><kwd>антивозрастной эффект</kwd><kwd>anti-aging</kwd><kwd>полифенолы</kwd><kwd>геропротекторы</kwd><kwd>клюква</kwd><kwd>брусника</kwd><kwd>черника</kwd><kwd>антиоксиданты</kwd><kwd>метаболический синдром</kwd><kwd>антимикробное действие</kwd><kwd>цитопротекторная активность</kwd><kwd>окислительный стресс</kwd><kwd>противовирусное действие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pathologic aging</kwd><kwd>anti-aging effect</kwd><kwd>polyphenols</kwd><kwd>geroprotectors</kwd><kwd>cranberries</kwd><kwd>lingonberries</kwd><kwd>blueberries</kwd><kwd>antioxidants</kwd><kwd>metabolic syndrome</kwd><kwd>antimicrobial action</kwd><kwd>cytoprotective activity</kwd><kwd>oxidative stress</kwd><kwd>antiviral effect</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">ПОТЕНЦИАЛ ГЕРОПРОТЕКТОРНОЙ АКТИВНОСТИ ПОЛИФЕНОЛОВ ТИПИЧНЫХ СЕВЕРНЫХ ЯГОД</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson R. 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