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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgumed</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник СурГУ. Медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Vestnik SurGU. Meditsina</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-3447</issn><publisher><publisher-name>Сургутский государственный университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">surgumed-165</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>СЫВОРОТОЧНЫЕ УРОВНИ БИОМАРКЕРА ГЕМОДИНАМИЧЕСКОГО СТРЕССА И МОРФОФУНКЦИОНАЛЬНЫЕ ИЗМЕНЕНИЯ ЛЕВОГО ЖЕЛУДОЧКА СЕРДЦА У ПАЦИЕНТОВ, ПЕРЕНЕСШИХ ИНФАРКТ МИОКАРДА С ПОДЪЕМОМ СЕГМЕНТА ST</article-title><trans-title-group xml:lang="en"><trans-title>SERUM LEVELS OF BIOMARKER OF HEMODYNAMIC STRESS AND MORPHOFUNCTIONAL CHANGESOF LEFT VENTRICLE IN PATIENTS WHO ENDURED ST-ELEVATED MYOCARDIAL INFARCTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyov</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">a.s.vorobyov@google.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваленко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalenko</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">lvkhome@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астраханцева</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Astrakhantseva</surname><given-names>I. D.</given-names></name></name-alternatives><email xlink:type="simple">astrakirina@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урванцева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Urvantseva</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">post@okd.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сургутский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Окружной кардиологический диспансер «Центр диагностики и сердечно-сосудистой хирургии», г. Сургут</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut District Cardiologic Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сургутский государственный университет; Окружной кардиологический диспансер «Центр диагностики и сердечно-сосудистой хирургии», г. Сургут</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Surgut State University; Surgut District Cardiologic Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>31</day><month>12</month><year>2018</year></pub-date><volume>0</volume><issue>4 (38)</issue><fpage>13</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Воробьев А.С., Коваленко Л.В., Астраханцева И.Д., Урванцева И.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Воробьев А.С., Коваленко Л.В., Астраханцева И.Д., Урванцева И.А.</copyright-holder><copyright-holder xml:lang="en">Vorobyov A.S., Kovalenko L.V., Astrakhantseva I.D., Urvantseva I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgumed.ru/jour/article/view/165">https://www.surgumed.ru/jour/article/view/165</self-uri><abstract><p>Цель - анализ литературы и клинических рекомендаций по диагностике, лечению и профилактике инфекции мочевой системы. Изучены клинические практические рекомендации (Российского диализного общества и KDIGO) нефрологов и детских урологов, проведен анализ опыта ведения детей с инфекциями мочевой системы с позиций доказательной медицины. В обзоре представлены современные зарубежные и отечественные данные по распространенности инфекции мочевой системы у детей различных возрастных групп. Описаны клинические формы и диагностические критерии данной патологии. Предложены алгоритмы лечения и противорецидивной терапии больных в зависимости от возраста, пола, наличия фоновых состояний и заболеваний, образа жизни.</p></abstract><trans-abstract xml:lang="en"><p>The goal of the article is to establish the relationship between indicators of the structure and function of the left ventricle in patients who have endured a myocardial infarction with ST-segment elevation. We examined the left ventricle during its post-infarction remodeling for 12 months with serum levels of NT-proBNP (N-Terminal proBrain Natriuretic Peptide), identified in the acute phase of myocardial infarction. In 108 patients with acute ST- elevated myocardial infarction, the biomarker is an amino-terminal fragment of the precursor of brain natriuretic peptide precursor. In patients with postinfarction left ventricular remodeling, the values of the NT-proBNP are higher (p = 0.03), which correlate with the degrees of systolic and diastolic dysfunction of the left ventricle (p &lt;0.05). The evaluation of this biomarker in the acute phase of myocardial infarction may be of clinical importance for the selection of patients at high risk of developing heart failure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>биомаркеры</kwd><kwd>ремоделирование</kwd><kwd>левый желудочек</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>biomarkers</kwd><kwd>remodeling</kwd><kwd>left ventricle</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Opie L. H., Commerford P. J. et al. Controversies in ventricular remodeling // Controvers Cardiol. 2006. Vol. 367. P. 33-44.</mixed-citation><mixed-citation xml:lang="en">Opie L. H., Commerford P. J. et al. Controversies in ventricular remodeling // Controvers Cardiol. 2006. Vol. 367. P. 33-44.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Galli A., Lombardi F. Postinfarct left ventricular remodeling: a prevailing cause of heart failure // Cardiology research and practice. 2016. Vol. 1. P. 1-12.</mixed-citation><mixed-citation xml:lang="en">Galli A., Lombardi F. Postinfarct left ventricular remodeling: a prevailing cause of heart failure // Cardiology research and practice. 2016. Vol. 1. P. 1-12.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Jarolim P. Overview of cardiac markers in heart disease // Clin Lab Med. 2014. Vol. 34 (1). P. 1-14.</mixed-citation><mixed-citation xml:lang="en">Jarolim P. Overview of cardiac markers in heart disease // Clin Lab Med. 2014. Vol. 34 (1). P. 1-14.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Жебель В. М., Пашкова Ю. П., Сакович О. О. и соавт. Клинические и клинико-генетические аспекты определения натрийуретического пептида у пациентов с хронической сердечной недостаточностью: достижения и перспективы // Серцева недостатність. 2016. № 1. С. 14-18.</mixed-citation><mixed-citation xml:lang="en">Жебель В. М., Пашкова Ю. П., Сакович О. О. и соавт. Клинические и клинико-генетические аспекты определения натрийуретического пептида у пациентов с хронической сердечной недостаточностью: достижения и перспективы // Серцева недостатність. 2016. № 1. С. 14-18.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Печерина Т. Б., Федорова Н. В., Герман А. И. и соавт. Клиническая значимость и динамика биомаркеров ремоделирования миокарда у больных инфарктом миокарда с подъемом сегмента ST и сохраненной функцией левого желудочка // Атеросклероз. 2018. Т. 14. № 1. С. 5-14.</mixed-citation><mixed-citation xml:lang="en">Печерина Т. Б., Федорова Н. В., Герман А. И. и соавт. Клиническая значимость и динамика биомаркеров ремоделирования миокарда у больных инфарктом миокарда с подъемом сегмента ST и сохраненной функцией левого желудочка // Атеросклероз. 2018. Т. 14. № 1. С. 5-14.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Федотова И. Н., Белопольский А. А., Стуров Н. В. Диагностическая значимость NT-proBNP у кардиологических больных // Трудный пациент. 2013. № 7. С. 32-25.</mixed-citation><mixed-citation xml:lang="en">Федотова И. Н., Белопольский А. А., Стуров Н. В. Диагностическая значимость NT-proBNP у кардиологических больных // Трудный пациент. 2013. № 7. С. 32-25.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ibanez B., James S. et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) // Eur Heart J. 2018. Vol. 7. № 39 (2). P. 119-177.</mixed-citation><mixed-citation xml:lang="en">Ibanez B., James S. et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) // Eur Heart J. 2018. Vol. 7. № 39 (2). P. 119-177.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hendriks T., Minke H., Hartman J. Predictors of left ventricular remodeling after ST-elevation myocardial infarction // Int J Cardiovasc Imaging. 2017. Vol. 33. P. 1415-1423.</mixed-citation><mixed-citation xml:lang="en">Hendriks T., Minke H., Hartman J. Predictors of left ventricular remodeling after ST-elevation myocardial infarction // Int J Cardiovasc Imaging. 2017. Vol. 33. P. 1415-1423.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ezekowitz J., Armstrong P., Granger C. et al. Predicting chronic left ventricular dysfunction 90 days after ST-segment elevation myocardial infarction: an assessment of pexelizumab in acute myocardial infarction (APEX-AMI) substudy // Am Heart J. 2010. Vol. 160. № 2. P. 272-278.</mixed-citation><mixed-citation xml:lang="en">Ezekowitz J., Armstrong P., Granger C. et al. Predicting chronic left ventricular dysfunction 90 days after ST-segment elevation myocardial infarction: an assessment of pexelizumab in acute myocardial infarction (APEX-AMI) substudy // Am Heart J. 2010. Vol. 160. № 2. P. 272-278.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Paelinck B., Vrints C., Bax J. et al. Relation of B-type natriuretic peptide early after acute myocardial infarction to left ventricular diastolic function and extent of myocardial damage determined by magnetic resonance imaging // Am J Cardiol. 2006. Vol. 97. P. 1146-1150.</mixed-citation><mixed-citation xml:lang="en">Paelinck B., Vrints C., Bax J. et al. Relation of B-type natriuretic peptide early after acute myocardial infarction to left ventricular diastolic function and extent of myocardial damage determined by magnetic resonance imaging // Am J Cardiol. 2006. Vol. 97. P. 1146-1150.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia-Alvarez A., Sitges M., Delgado V. et al. Relation of plasma brain natriuretic peptide levels on admission for ST-elevation myocardial infarction to left ventricular end-diastolic volume six months later measured by both echocardiography and cardiac magnetic resonance // Am J Cardiol. 2009. Vol. 104. P. 878-882.</mixed-citation><mixed-citation xml:lang="en">Garcia-Alvarez A., Sitges M., Delgado V. et al. Relation of plasma brain natriuretic peptide levels on admission for ST-elevation myocardial infarction to left ventricular end-diastolic volume six months later measured by both echocardiography and cardiac magnetic resonance // Am J Cardiol. 2009. Vol. 104. P. 878-882.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Flachskampf F. A., Schmid M., Rost C. et al. Cardiac imaging after myocardial infarction // Eur Heart J. 2011. Vol. 32. № 3. P. 272-283.</mixed-citation><mixed-citation xml:lang="en">Flachskampf F. A., Schmid M., Rost C. et al. Cardiac imaging after myocardial infarction // Eur Heart J. 2011. Vol. 32. № 3. P. 272-283.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Hirayama A., Kusuoka H., Yamamoto H. et al. Usefulness of plasma brain natriuretic peptide concentration for predicting subsequent left ventricular remodeling after coronary angioplasty in patients with acute myocardial infarction // Am J Cardiol. 2006 Vol. 98. P. 453-457.</mixed-citation><mixed-citation xml:lang="en">Hirayama A., Kusuoka H., Yamamoto H. et al. Usefulness of plasma brain natriuretic peptide concentration for predicting subsequent left ventricular remodeling after coronary angioplasty in patients with acute myocardial infarction // Am J Cardiol. 2006 Vol. 98. P. 453-457.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Cochet A., Zeller M., Cottin Y. et al. The extent of myocardial damage assessed by contrast-enhanced MRI is a major determinant of N-BNP concentration after myocardial infarction // Eur J Heart Fail. 2004. Vol. 6. P. 555-560.</mixed-citation><mixed-citation xml:lang="en">Cochet A., Zeller M., Cottin Y. et al. The extent of myocardial damage assessed by contrast-enhanced MRI is a major determinant of N-BNP concentration after myocardial infarction // Eur J Heart Fail. 2004. Vol. 6. P. 555-560.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Joost D., Niels J., Wichert J. et al. Comparison of Usefulness of N-Terminal Pro-Brain Natriuretic Peptide as an Independent Predictor of Cardiac Func tion Among Admission Cardiac Serum Biomarkers in Patients With Anterior Wall Versus Nonanterior Wall ST-Segment Elevation Myocardial Infarction Undergoing Primar y Percutaneous Coronary Intervention // Am J Cardiol. 2010. Vol. 105 (8). P. 1065-1069.</mixed-citation><mixed-citation xml:lang="en">Joost D., Niels J., Wichert J. et al. Comparison of Usefulness of N-Terminal Pro-Brain Natriuretic Peptide as an Independent Predictor of Cardiac Func tion Among Admission Cardiac Serum Biomarkers in Patients With Anterior Wall Versus Nonanterior Wall ST-Segment Elevation Myocardial Infarction Undergoing Primar y Percutaneous Coronary Intervention // Am J Cardiol. 2010. Vol. 105 (8). P. 1065-1069.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Ang D., Kong C., Kao M. et al. Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronar y syndrome independent of echocardiographic abnormalities // Am Heart J. 2009. Vol. 158 (1). P. 133-40.</mixed-citation><mixed-citation xml:lang="en">Ang D., Kong C., Kao M. et al. Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronar y syndrome independent of echocardiographic abnormalities // Am Heart J. 2009. Vol. 158 (1). P. 133-40.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Vogiatzis I., Dapcevic I., Datsios A. et al. A Comparison of Prognostic Value of the Levels of ProBNP and Troponin T in Patients with Acute Coronary Syndrome (ACS) // Med Arch. 2016. Vol. 70 (4). P. 269-273.</mixed-citation><mixed-citation xml:lang="en">Vogiatzis I., Dapcevic I., Datsios A. et al. A Comparison of Prognostic Value of the Levels of ProBNP and Troponin T in Patients with Acute Coronary Syndrome (ACS) // Med Arch. 2016. Vol. 70 (4). P. 269-273.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Лузин В. Г., Урванцева И. А., Ковальчук Д. Н. и соавт. Анализ влияния прогноз-негативных факторов на госпитальную смертность у пациентов с острым инфарктом миокарда, перенесших ургентное коронарное шунтирование // Вестник СурГУ. Медицина. 2017. № 2. С. 36-38.</mixed-citation><mixed-citation xml:lang="en">Лузин В. Г., Урванцева И. А., Ковальчук Д. Н. и соавт. Анализ влияния прогноз-негативных факторов на госпитальную смертность у пациентов с острым инфарктом миокарда, перенесших ургентное коронарное шунтирование // Вестник СурГУ. Медицина. 2017. № 2. С. 36-38.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
